Hydrogels - Recent Advances

Hydrogels - Recent Advances
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水凝胶 - 最新进展

DOI:
10.1007/978-981-10-6077-9_1
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发表时间:
2018
期刊:
--
影响因子:
--
通讯作者:
Novakovic K
Novakovic K
中科院分区:
--
文献类型:
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作者:
Novakovic K

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药物递送系统(DDS)可以定义为促进治疗物质在体内释放的制剂或装置。DDS的关键参数是安全性、递送速率、效率以及药物释放的时间和地点。近年来,水凝胶在药物释放方面的应用引起了人们的极大关注。它们的特征在于具有多孔性、孔径和几何形状的多孔结构,其可以在水凝胶合成期间变化。重要的是,由于多孔结构,它们具有掺入生物分子的能力。
A drug delivery system (DDS)can be defined as a formulation or a device that facilitates the release of a therapeutic substance in the body. Key parameters of interest in DDS are safety, delivery rate, efficiency, as well as time and place of release of drugs. Lately, hydrogels have attracted significant attention for application in drug delivery.Hydrogelsare three-dimensional polymer networks consisting largely of water. They are characterised by a porous structure with porosity, pore size and geometry that can be varied during the hydrogel synthesis. Importantly, due to porous structure they have the ability to incorporate biomolecules.