Socioeconomic status and gastric cancer survival in Japan
Socioeconomic status and gastric cancer survival in Japan
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DOI：
10.1007/s10120-010-0561-4
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发表时间：
2010-11-01
期刊：
影响因子：
7.4
通讯作者：
Tsugane, Shoichiro
中科院分区：
文献类型：
--
作者：
Kuwahara, Aya;Takachi, Ribeka;Tsugane, Shoichiro
很少有研究调查日本癌症患者的社会经济地位与生存之间的关系。我们在一项正在进行的大型人群队列研究中检查了职业或教育水平是否与 725 名被诊断出的胃癌患者的生存相关。在调整诊断年龄和性别后，我们发现，与专业人士或办公室工作人员相比，失业受试者（风险比 [HR]，2.23；95% 置信区间） [CI]，1.27-3.92）和体力劳动者（HR，1.68；95% CI，1.07-2.62）胃癌死亡风险增加。在进一步调整临床疾病范围后，增加的风险消失了。教育水平与风险无关。这些研究结果表明，日本胃癌患者的职业生存率存在差异，这主要是由于失业者和体力劳动者中早期疾病的比例较低。
Few studies have investigated the association between socioeconomic status and the survival of cancer patients in Japan.We examined whether occupation or educational level was associated with the survival of 725 gastric cancer patients who were diagnosed within an ongoing large population-based cohort study.After adjustment for age at diagnosis, and sex, we found that, compared with professionals or office workers, unemployed subjects (hazard ratio [HR], 2.23; 95% confidence interval [CI], 1.27-3.92) and manual laborers (HR, 1.68; 95% CI, 1.07-2.62) had an increased risk of gastric cancer death. After further adjustment for the clinical extent of disease, the increased risk disappeared. Educational level was not associated with the risk.These findings suggest that a disparity in survival by occupation exists among Japanese gastric cancer patients, largely due to a lower proportion of early disease among the unemployed and manual laborers.