Delayed Gadolinium-Enhanced Magnetic Resonance Imaging (dGEMRIC) of Hip Joint Cartilage in Femoroacetabular Impingement (FAI): Are Pre- and Postcontrast Imaging Both Necessary?
Delayed Gadolinium-Enhanced Magnetic Resonance Imaging (dGEMRIC) of Hip Joint Cartilage in Femoroacetabular Impingement (FAI): Are Pre- and Postcontrast Imaging Both Necessary?
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DOI：
10.1002/mrm.22166
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发表时间：
2009-12-01
影响因子：
3.3
通讯作者：
Mamisch, Tallal C.
中科院分区：
文献类型：
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作者：
Bittersohl, Bernd;Hosalkar, Harish S.;Mamisch, Tallal C.
本研究的目的是评估使用对比后 T(1) (T(1Gd)) 的软骨延迟钆 MRI 是否足以在不使用非对比值 (T(10)) 的情况下评估股骨髋臼撞击中的软骨损伤。 T(1Gd) 和 Delta R(1) (1/T(1Gd) - 1/T(10))（包括非对比 T(1) 测量）在两个级别的骨关节炎和无症状年轻成年志愿者的对照组中进行了研究。比较股骨髋臼撞击患者和志愿者的 T(1Gd) 和 Delta R(1) 值之间的差异。在所有研究组中，T(1Gd) 和 Delta R(1) 之间存在非常高的相关性。在 Tonnis 0 级的研究队列中，无症状志愿者中 Tonnis 1 级的相关性 (r) 为 -0.95 和 -0.89，相关性 (r) 为 -0.88，所有组均具有统计学显着性 (P < 0.001)。对于 T(1Gd) 和 Delta R(1)，患者和对照组之间存在统计学显着差异。 Tonnis 0 级骨关节炎患者和 1 级骨关节炎患者之间的 T(1Gd) 和 Delta R(1) 也存在显着差异。我们的结果证明 T(1Gd) 和 Delta R(1) 之间存在线性相关性，表明 T(1Gd) 评估足以在这种情况下对软骨延迟钆 MRI 进行临床应用，并且可能不需要额外耗时的 T(10) 评估。 Magn Reson Med 62:1362-1367, 2009。(C) 2009 Wiley-Liss, Inc.
The purpose of this study was to assess if delayed gadolinium MRI of cartilage using postcontrast T(1) (T(1Gd)) is sufficient for evaluating cartilage damage in femoroacetabular impingement without using noncontrast values (T(10)). T(1Gd) and Delta R(1) (1/T(1Gd) - 1/T(10)) that include noncontrast T(1) measurements were studied in two grades of osteoarthritis and in a control group of asymptomatic young-adult volunteers. Differences between T(1Gd) and Delta R(1) values for femoroacetabular impingement patients and volunteers were compared. There was a very high correlation between T(1Gd) and Delta R(1) in all study groups. In the study cohort with Tonnis grade 0, correlation (r) was -0.95 and -0.89 with Tonnis grade 1 and -0.88 in asymptomatic volunteers, being statistically significant (P < 0.001) for all groups. For both T(1Gd) and Delta R(1), a statistically significant difference was noted between patients and control group. Significant difference was also noted for both T(1Gd) and Delta R(1) between the patients with Tonnis grade 0 osteoarthritis and those with grade 1 changes. Our results prove a linear correlation between T(1Gd) and Delta R(1), suggesting that T(1Gd) assessment is sufficient for the clinical utility of delayed gadolinium MRI of cartilage in this setting and additional time-consuming T(10) evaluation may not be needed. Magn Reson Med 62:1362-1367, 2009. (C) 2009 Wiley-Liss, Inc.