Pelvic organ prolapse in the Women's Health Initiative: Gravity and gravidity

Pelvic organ prolapse in the Women's Health Initiative: Gravity and gravidity
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DOI:
10.1067/mob.2002.123819
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发表时间:
2002-06-01
影响因子:
9.8
通讯作者:
McTiernan, A
McTiernan, A
中科院分区:
医学1区
文献类型:
--
作者:
Hendrix, SL;Clark, A;McTiernan, A

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目的:本研究的目的是描述的患病率和相关的盆腔器官prolongation.Study设计:这是一个横断面分析的妇女谁参加了妇女健康倡议激素替代疗法临床试验(n = 27,342名妇女)。基线问卷调查确定人口统计学和个人习惯。基线盆腔检查评估子宫脱垂、膀胱膨出和直肠前突。采用描述性统计和Logistic回归模型研究与盆腔器官脱垂相关的因素。结果:在16,616名有子宫的妇女中,子宫脱垂的发生率为14.2%,膀胱膨出的发生率为34.3%,直肠前突的发生率为18.6%。在10,727例接受子宫切除术的妇女中,膀胱膨出的患病率为32.9%,直肠前突的患病率为18.3%。在控制了年龄、体重指数和其他健康/身体变量后,非裔美国妇女的脱垂风险最低。西班牙裔妇女发生子宫脱垂的风险最高。产次和肥胖与子宫脱垂、膀胱膨出和直肠前突的风险增加密切相关。结论:盆腔器官脱垂是老年妇女的常见疾病。脱垂的风险在不同种族群体之间存在差异,这表明风险因素修改和预防的方法也可能不同。这些数据将有助于满足不同人群的妇科需求。
OBJECTIVE: The purpose of this study was to describe the prevalence of and correlates for pelvic organ prolapse.STUDY DESIGN: This was a cross-sectional analysis of women who enrolled in the Women's Health Initiative Hormone Replacement Therapy Clinical Trial (n = 27,342 women). Baseline questionnaires ascertained demographics and personal habits. A baseline pelvic examination assessed uterine prolapse, cystocele, and rectocele. Descriptive statistics and logistic regression models were used to investigate factors that were associated with pelvic organ prolapse.RESULTS: In the 16,616 women with a uterus, the rate of uterine prolapse was 14.2%; the rate of cystocele was 34.3%; and the rate of rectocele was 18.6%. For the 10,727 women who had undergone hysterectomy, the prevalence of cystocele was 32.9% and of rectocele was 18.3%. After controlling for age, body mass index, and other health/physical variables, African American women demonstrated the lowest risk for prolapse. Hispanic women had the highest risk for uterine prolapse. Parity and obesity were strongly associated with increased risk for uterine prolapse, cystocele, and rectocele.CONCLUSION: Pelvic organ prolapse is a common condition in older women. The risk for prolapse differs between ethnic groups, which suggests that the approaches to risk-factor modification and prevention may also differ. These data will help address the gynecologic needs of diverse populations.