Inhibition by chlorpromazine of the effects of dopamine on the dog kidney
Inhibition by chlorpromazine of the effects of dopamine on the dog kidney
复制标题
氯丙嗪抑制多巴胺对狗肾脏的影响
DOI：
10.1111/j.2042-7158.1970.tb12750.x
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发表时间：
1970
期刊：
影响因子：
--
通讯作者：
Giovanni Brotzu
中科院分区：
文献类型：
--
作者：
Giovanni Brotzu
多巴胺诱导的犬肾动脉血管舒张可被氯丙嗪逆转，而异丙肾上腺素产生的血管舒张则不可。扑热息痛对本制剂有完全相反的作用。将多巴胺输注到肾动脉中增强了水、钠、钾和尿素的肾脏输出。这些作用也被氯丙嗪逆转。
Dopamine‐induced vasodilatation in the renal artery of the dog is reversed by chlorpromazine while the vasodilatation produced by isoprenaline is not. Pronethalol has the entirely opposite actions on this preparation. The infusion of dopamine into the renal artery enhances the kidney output of water, sodium, potassium and urea. These effects are also reversed by chlorpromazine.