Impact of left ventricular systolic function on clinical and echocardiographic outcomes following transcatheter aortic valve implantation for severe aortic stenosis
Impact of left ventricular systolic function on clinical and echocardiographic outcomes following transcatheter aortic valve implantation for severe aortic stenosis
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DOI：
10.1016/j.ahj.2010.09.003
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发表时间：
2010-12-01
影响因子：
4.8
通讯作者：
Bax, Jeroen J.
中科院分区：
文献类型：
--
作者：
Ewe, See Hooi;Marsan, Nina Ajmone;Bax, Jeroen J.
本研究旨在评价基线左心室（LV）收缩功能对经导管主动脉瓣植入术（TAVI）后临床和超声心动图结局的影响。接受TAVI的患者的生存率进行了比较，人口接受外科主动脉瓣replacement.Methods一百四十七个连续患者（平均年龄= 80 +/- 7岁）接受TAVI在2个中心。平均随访时间为9.1 ± 5.1个月。结果基线时，34%的患者左室射血分数（LVEF）受损（≥ 50%）。这两组的手术成功率相似（94% vs 97%，P = 0.41）。所有患者的跨瓣血流动力学均得到改善。随访时，基线LVEF
Background This study aimed to evaluate the impact of baseline left ventricular (LV) systolic function on clinical and echocardiographic outcomes following transcatheter aortic valve implantation (TAVI). Survival of patients undergoing TAVI was also compared with that of a population undergoing surgical aortic valve replacement.Methods One hundred forty-seven consecutive patients (mean age = 80 +/- 7 years) undergoing TAVI in 2 centers were included. Mean follow-up period was 9.1 +/- 5.1 months.Results At baseline, 34% of patients had impaired LV ejection fraction (LVEF) (= 50%). Procedural success was similar in these 2 groups (94% vs 97%, P = .41). All patients achieved improvement in transvalvular hemodynamics. At follow-up, patients with a baseline LVEF