Regulatory T cells: immune suppression and beyond.

Regulatory T cells: immune suppression and beyond.
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DOI:
10.1038/cmi.2010.20
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发表时间:
2010-05
影响因子:
24.1
通讯作者:
--
中科院分区:
医学1区
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--
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Foxp3-expressing regulatory T cells (Tregs) were originally identified as critical in maintaining self-tolerance and immune homeostasis. The immunosuppressive functions of Tregs are widely acknowledged and have been extensively studied. Recent studies have revealed many diverse roles of Tregs in shaping the immune system and the inflammatory response. This review will discuss our efforts as well as the efforts of others towards understanding the multifaceted function of Tregs in immune regulation.
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