AN UPDATE ON INCIDENCE OF FAS - FAS IS NOT AN EQUAL-OPPORTUNITY BIRTH-DEFECT

AN UPDATE ON INCIDENCE OF FAS - FAS IS NOT AN EQUAL-OPPORTUNITY BIRTH-DEFECT
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DOI:
10.1016/0892-0362(95)00005-c
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发表时间:
1995-07-01
影响因子:
2.9
通讯作者:
ABEL, EL
ABEL, EL
中科院分区:
医学3区
文献类型:
--
作者:
ABEL, EL

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胎儿酒精综合症的发病率目前估计为普通产科人口中每1 000例活产0.97例,“重度”饮酒者中为4.3%。美国的总发病率(1.95/1000)比欧洲和其他国家(0.08/1000)高20倍以上。在美国,以低社会经济地位和非裔美国人或美洲原住民背景为特征的研究中心的发病率(2.29例/1,000)比以中/上SES和高加索背景为主的研究中心(0.26例/1,000)高出约10倍。根据种族背景,美国每年有2,043名孕妇生下FAS儿童;如果根据社会经济地位,这个数字略高2,366。虽然在美国的研究中种族和社会经济地位是混淆的,但对美国和欧洲研究的检查表明,与FAS相关的主要因素是低社会经济地位,而不是种族背景。
The incidence of Fetal Alcohol Syndrome is now estimated at 0.97 cases per 1,000 live births in the general obstetric population and 4.3% among ''heavy'' drinkers. The general incidence is more than 20 times higher in the United States (1.95 per 1,000) compared to Europe and other countries (0.08 per 1,000). Within the United States, the incidence at sites characterized by low socioeconomic status, and African American or Native American background are about 10 times higher (2.29 cases per 1,000) compared to sites with a predominant middle/upper SES and Caucasian background (0.26 per 1,000). Based on racial background, the number of pregnant women in the U.S. giving birth to FAS children is 2,043 per year; if based on socioeconomic status, the number is slightly higher 2,366. Although race and SES are confounded in the U.S. studies, an examination of U.S. and European studies suggests that the major factor associated with FAS is low SES rather than racial background.