Results of catheter ablation of typical atrial flutter
Results of catheter ablation of typical atrial flutter
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DOI：
10.1016/j.amjcard.2004.04.058
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发表时间：
2004-08-15
影响因子：
2.8
通讯作者：
Onufer, J
中科院分区：
文献类型：
--
作者：
Calkins, H;Canby, R;Onufer, J
本研究的目的是评价使用8 mm电极导管和100 W射频功率发生器射频消融典型心房扑动的安全性和有效性。以前的房扑导管消融试验的局限性是数据不是作为前瞻性多中心临床试验的一部分收集的。研究结果显示，在150例患者中，导管消融典型房扑的急性有效率为88%。6个月随访时，13%的患者观察到复发性典型房扑。12例典型房扑复发患者中，4例有症状，8例无症状。手术持续时间是典型房扑复发的重要预测因素。12个月房颤发生率为30%。心房扑动导管消融与简明36调查表（生活质量）8个领域中的5个领域的显著改善相关，症状自评量表16个症状中的13个症状显著降低。器械或手术相关并发症发生率为2.7%。3例患者由于较强的射频功率在分散垫部位发生皮肤灼伤。使用双分散垫系统缓解了这个问题。因此，本研究的结果表明，心房扑动的导管消融具有较高的急性疗效，复发性心房扑动的风险较小，随访期间房颤的风险较大。(C)2004年，Excerpta Medica，Inc.
The purpose of this study was to evaluate the safety and efficacy of radiofrequency (RF) ablation of typical atrial flutter by using an 8-mm electrode catheter and a 100-W RF power generator. A limitation of previous trials of catheter ablation of atrial flutter is that the data were not collected as part of a prospective multicenter clinical trial. The study results associated catheter ablation of typical atrial flutter in a cohort of 150 patients with an 88% acute efficacy rate. At 6-month follow-up, recurrent typical atrial flutter was observed in 13% of patients. Of the 12 patients with typical atrial flutter recurrence, 4 were symptomatic and 8 were asymptomatic. Procedure duration was a significant predictor of typical atrial flutter recurrence. The 12-month rate for development of atrial fibrillation was 30%. Catheter ablation of atrial flutter was associated with significant improvements in 5 of 8 domains of the Short Form 36 Survey (quality of life) and significant decreases in 13 of the 16 symptoms of the Symptom Checklist. The device- or procedure-related complication rate was 2.7%. Skin burns occurred at the dispersive pad site due to stronger RF power in 3 patients. Use of a dual dispersive pad system mitigated this problem. Thus, the results of this study associated catheter ablation of atrial flutter with high acute efficacy, a small risk of recurrent atrial flutter, and an important risk of atrial fibrillation during follow-up. (C) 2004 by Excerpta Medica, Inc.