Blood volume changes and high and low pressoreceptor activity in cats.

Blood volume changes and high and low pressoreceptor activity in cats.
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猫的血容量变化和高、低压力感受器活性。

DOI:
10.1152/ajpregu.1984.247.5.r833
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发表时间:
1984
期刊:
The American journal of physiology
影响因子:
--
通讯作者:
Gilmore,JP
Gilmore,JP
中科院分区:
--
文献类型:
--
作者:
Tomomatsu,E;Gilmore,JP

文献摘要

被引文献

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在猫身上进行了研究,以确定中度出血或容量扩张是否显著改变了颈动脉窦和主动脉压力感受器的活性。此外,实验设计提供了比较两组受体的增益的机会。20%血容量扩张使平均动脉压增加5.2%,颈动脉窦神经活动增加14.7%,而20%血容量扩张使平均动脉压降低10.8%,颈动脉窦神经活动减少32.3%。对于主动脉压力感受器,20%的血容量扩张使平均动脉压和神经活动增加5.9%和10.5%,而20%的出血使平均动脉压和神经活动减少8.9%和21.0%。颈动脉窦和主动脉压力感受器的血压-放电曲线没有不同。众所周知,心房感受器的高敏感性也被记录在案。我们认为,高、低压受体均可调节中枢神经系统的血管内容量和压力状态。
Studies were undertaken in the cat to determine if moderate hemorrhage or volume expansion significantly altered carotid sinus and aortic baroreceptor activity. In addition, the experimental design provided the opportunity to compare gain of the two sets of receptors. A 20% blood volume expansion increased mean arterial blood pressure 5.2% and carotid sinus nerve activity 14.7%, whereas a 20% hemorrhage decreased mean arterial blood pressure 10.8% and carotid sinus nerve activity 32.3%. For the aortic baroreceptors, a 20% blood volume expansion increased mean arterial blood pressure 5.9% and nerve activity 10.5%, and a 20% hemorrhage decreased mean arterial blood pressure 8.9% and nerve activity 21.0%. The blood pressure-discharge curves for the carotid sinus and aortic baroreceptors were not different. The well-known high sensitivity of atrial receptors was also documented. We conclude that both high- and low-pressure receptors apprise the central nervous system of the status of intravascular volume and pressure.