A program for treating olanzapine-related weight gain
A program for treating olanzapine-related weight gain
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DOI：
10.1176/appi.ps.52.7.967
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发表时间：
2001-07-01
影响因子：
3.8
通讯作者：
Buchanan, RW
中科院分区：
文献类型：
--
作者：
Ball, MP;Coons, VB;Buchanan, RW
本研究评估了体重观察者计划对患有奥氮平相关体重增加的精神分裂症患者的有效性，并确定患者精神症状的严重程度是否与患者减肥成功相关。7名男性和4名女性接受了奥氮平治疗，体重增加了至少7%，他们参加了减肥观察者会议，并接受了监督锻炼。对患者的体重、体重指数和精神症状进行评估，并与未参加慧俪轻体计划的匹配对照组进行比较。只有男性经历了显著的体重减轻。没有发现体重减轻和运动或精神症状的变化之间的相关性。
This study evaluated the effectiveness of a Weight Watchers program for patients with schizophrenia who had olanzapine-related weight gain and ascertained whether the severity of patients' psychiatric symptoms was correlated with the patients' success in losing weight. Seven men and four women who had been treated with olanzapine and who had gained at least 7 percent of their pretreatment body weight attended Weight Watchers meetings and were offered supervised exercise sessions. The patients' weight, body mass index, and psychiatric symptoms were assessed and were compared with those of a matched comparison group who did not attend the Weight Watchers program. Only the men experienced significant weight loss. No correlation was found between weight loss and exercise or change in psychiatric symptoms.