HIGHLY ENANTIOSELECTIVE CATALYTIC DIELS-ALDER ADDITION PROMOTED BY A CHIRAL BIS(OXAZOLINE)-MAGNESIUM COMPLEX
HIGHLY ENANTIOSELECTIVE CATALYTIC DIELS-ALDER ADDITION PROMOTED BY A CHIRAL BIS(OXAZOLINE)-MAGNESIUM COMPLEX
复制标题
DOI：
10.1016/s0040-4039(00)61781-1
复制
发表时间：
1992-11-03
影响因子：
1.8
通讯作者：
ISHIHARA, K
中科院分区：
文献类型：
--
作者：
COREY, EJ;ISHIHARA, K
新的手性双（恶唑啉）配体8已经由（S）-苯基甘氨酸合成，并且已经被证明与碘化铁、碘化镁或四苯基硼酸镁组合形成对映选择性Diels-Alder加成的有效催化剂。在镁体系中，亲二烯体3-丙烯酰基-1，3-恶唑烷-2-酮（4）的催化活化涉及四面体配位的镁形成双正配合物（10）。
The new chiral bis(oxazoline) ligand 8 has been synthesized from (S)-phenylglycine and has been shown to form effective catalysts for enantioselective Diels-Alder addition in combination with ferric iodide, magnesium iodide or magnesium tetraphenylborate. Catalytic activation of the dienophile, 3-acryloyl-1,3-oxazolidine-2-one (4), in the magnesium system is proposed to involve tetrahedrally coordinated magnesium in a dipositive complex (10).