Day-to-day dynamics of experience-cortisol associations in a population-based sample of older adults
Day-to-day dynamics of experience-cortisol associations in a population-based sample of older adults
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DOI：
10.1073/pnas.0605053103
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发表时间：
2006-11-07
影响因子：
11.1
通讯作者：
Cacioppo, John T.
中科院分区：
文献类型：
--
作者：
Adam, Emma K.;Hawkley, Louise C.;Cacioppo, John T.
在156名老年人中，从上一天和当天的经验都可以预测皮质醇昼夜节奏的日常变化，以检查自然主义环境中经验 - 质子溶液关联的时间顺序。每天的心理社会，情感和身体状态的日记报告连续三天都在睡前完成。唾液皮质醇水平在唤醒时测量，觉醒后30分钟，每天就睡前测量。多级生长曲线模型用于每天估计每个人的昼夜皮质醇谱。从白天和当天的体验中同时预测了定义这些配置文件的参数（唤醒水平，昼夜斜率和皮质醇觉醒响应）。第二天，第二天的孤独感，悲伤，威胁和缺乏控制的感觉与第二天的皮质醇觉醒反应有关，但是早晨觉醒的反应并没有预测当天晚些时候这些州的经历。同一天，但不是前，紧张和愤怒的感觉与柔抗皮质醇的节奏相关，主要是因为它们与高级Sameday晚上皮质醇水平的关联。尽管唤醒皮质醇水平并未通过疲劳和身体症状的早期水平预测，但低唤醒皮质醇预测当天晚些时候较高的疲劳和身体症状。结果与皮质醇的动态和交易功能一致，这既是对生理激活的社会心理和情感体验的传感器，也是对能量和身体健康感的影响。
In 156 older adults, day-to-day variations in cortisol diurnal rhythms were predicted from both prior-day and same-day experiences, to examine the temporal ordering of experience-cortisol associations in naturalistic environments. Diary reports of daily psychosocial, emotional, and physical states were completed at bedtime on each of three consecutive days. Salivary cortisol levels were measured at wakeup, 30 min after awakening, and at bedtime each day. Multilevel growth curve modeling was used to estimate diurnal cortisol profiles for each person each day. The parameters defining those profiles (wakeup level, diurnal slope, and cortisol awakening response) were predicted simultaneously from day-before and same-day experiences. Prior-day feelings of loneliness, sadness, threat, and lack of control were associated with a higher cortisol awakening response the next day, but morning awakening responses did not predict experiences of these states later the same day. Same-day, but not prior-day, feelings of tension and anger were associated with flatter diurnal cortisol rhythms, primarily because of their association with higher sameday evening cortisol levels. Although wakeup cortisol levels were not predicted by prior-day levels of fatigue and physical symptoms, low wakeup cortisol predicted higher levels of fatigue and physical symptoms later that day. Results are consistent with a dynamic and transactional function of cortisol as both a transducer of psychosocial and emotional experience into physiological activation and an influence on feelings of energy and physical well-being.