Source monitoring and memory confidence in schizophrenia

Source monitoring and memory confidence in schizophrenia
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DOI:
10.1017/s0033291702006852
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发表时间:
2003-01-01
影响因子:
6.9
通讯作者:
Ruff, CC
Ruff, CC
中科院分区:
医学1区
文献类型:
--
作者:
Moritz, S;Woodward, TS;Ruff, CC

文献摘要

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背景本研究试图扩展以前的研究精神分裂症的源监控缺陷。我们假设,患者会表现出一种偏见,将自我生成的单词归因于外部来源。此外,预计精神分裂症患者会对错误记忆归因过度自信。30名精神分裂症患者和21名健康受试者被要求提供20个单词的语义关联。随后,研究人员阅读了一份包含实验者和自己生成的单词以及新词的列表。受试者被要求识别每个项目为旧/新,名称的来源,并说明来源属性的置信度。精神分裂症患者显示出显着增加的来源归因错误的数量,并显着更有信心比控制,一个错误的来源归因反应是真实的。后者的偏见得到改善,高剂量的抗精神病药物。据推测,核心认知缺陷潜在的精神分裂症是一个失败的区分从真正的记忆内容的错误。
Background. The present study attempted to extend previous research on source monitoring deficits in schizophrenia. We hypothesized that patients would show a bias to attribute self-generated words to an external source. Furthermore, it was expected that schizophrenic patients would be overconfident regarding false memory attributions.Method. Thirty schizophrenic and 21 healthy participants were instructed to provide a semantic association for 20 words. Subsequently, a list was read containing experimenter- and self-generated words as well as new words. The subject was required to identify each item as old/new, name the source, and state the degree of confidence for the source attribution.Results. Schizophrenic patients displayed a significantly increased number of source attribution errors and were significantly more confident than controls that a false source attribution response was true. The latter bias was ameliorated by higher doses of neuroleptics.Conclusions. It is inferred that a core cognitive deficit underlying schizophrenia is a failure to distinguish false from true mnestic contents.