SyphilisCardiovascular Manifestations of the Great Imitator
SyphilisCardiovascular Manifestations of the Great Imitator
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DOI：
10.1111/1556-4029.13709
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发表时间：
2018-07-01
影响因子：
1.6
通讯作者：
Byard, Roger W.
中科院分区：
文献类型：
--
作者：
Byard, Roger W.
梅毒的发病率再次开始上升，世界卫生组织估计，近年来每年有1200万例梅毒新发病例; 2002年，梅毒占全球死亡人数的0.3%。高危人群包括年轻男性（20- 29岁）、囚犯和性工作者。年轻女性发病率的增加增加了先天性病例的数量。对阿德莱德大学病理学档案的审查发现了4例具有显著病理学的病例，包括心脏树胶肿和主动脉弓动脉瘤。这些病例显示了未经治疗的三期梅毒的心血管特征。这种晚期病理的病例只会发生在尚未作出诊断和/或在疾病早期未实施标准抗生素治疗的情况下。
Rates of syphilis are beginning to once again increase, with the World Health Organization estimating that in recent years there were 12 million new cases of syphilis each year; in 2002, syphilis was responsible for 0.3% of deaths globally. At-risk groups include young males (20-29years), prisoners, and sex workers. Increased rates in young females have elevated the numbers of congenital cases. Review of the University of Adelaide Pathology Archive revealed four cases with significant pathology, which included cardiac gummas and aortic arch aneurysms. These cases demonstrate the cardiovascular characteristics of untreated syphilis in the tertiary stage. Cases with such advanced pathology will only occur where diagnoses have not been made, and/or standard antibiotic therapy has not been implemented in the early stage of disease.