Assessment of the impact of an exercise program on the physical and functional capacity in patients with autosomal recessive spastic ataxia of Charlevoix-Saguenay: An exploratory study
Assessment of the impact of an exercise program on the physical and functional capacity in patients with autosomal recessive spastic ataxia of Charlevoix-Saguenay: An exploratory study
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DOI：
10.5582/irdr.2018.01060
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发表时间：
2018-08-01
影响因子：
1.3
通讯作者：
Leone, Mario
中科院分区：
文献类型：
--
作者：
Audet, Olivier;Hung Tien Bui;Leone, Mario
常染色体隐性痉挛性共济失调（ARSACS）是一种由SACS基因突变引起的神经肌肉疾病。该病的临床症状包括进行性共济失调、痉挛和周围神经病变。与其他神经肌肉疾病类似，这些患者容易出现身体状况下降，从而可能导致功能丧失。本文旨在评价一种训练方案对ARSACS患者身体素质和功能能力的影响。12例患者（年龄：28.1±8.2岁）参加了本研究。他们接受了为期八周的训练计划，包括体力活动、力量训练和有氧训练。与最初的评估相比，身体健康和功能能力的测量显着改善(p
Autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) is a neuromuscular disorder caused by the mutation of the SACS gene. Clinical symptoms of this disease include progressive ataxia, spasticity, and peripheral neuropathy. Similar to other neuromuscular disorders, these patients are prone to physical deconditioning which may lead to a loss of functional capacity. This paper aims to evaluate the impact of a training program on the physical fitness and the functional capacity of ARSACS patients. Twelve patients (age: 28.1 +/- 8.2 years) participated in this study. They followed an eight-week training program including physical activities, strength-power and aerobic training. Compared to the initial evaluation, measures of physical fitness and functional capacity were significantly improved (p