LUCIDULINE - A UNIQUE TYPE OF LYCOPODIUM ALKALOID
LUCIDULINE - A UNIQUE TYPE OF LYCOPODIUM ALKALOID
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DOI：
10.1139/v68-602
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发表时间：
1968-01-01
期刊：
影响因子：
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通讯作者：
NKUNIKA, DS
中科院分区：
文献类型：
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作者：
AYER, WA;MASAKI, N;NKUNIKA, DS
本文报道了存在于黄连弱碱中的生物碱luciduline C13H21ON的分离和结构的测定。给出了化学和物理证据，证明了luciduline的结构。x射线衍射研究证实了这一假设，并确定了C-8甲基的立体化学。因此，luciduline的完整结构，包括绝对构型，用1表示。本文讨论了一种新型黄连二生物碱——luciduline的生物合成方法。用结构解释了luciduline及其衍生物的质谱。
The isolation and determination of the structure of luciduline, C13H21ON, an alkaloid present among the weak bases ofLycopodiumlucidulumMichx, is described. Chemical and physical evidence which suggests structure9for luciduline is presented. An X-ray diffraction study onO-p-bromobenzoyl-dihydroluciduline confirmed this hypothesis and defined the stereochemistry of the methyl group at C-8. The complete structure of luciduline, including absolute configuration, is thus represented by1. A possible mode of biosynthesis of luciduline, which is a new type ofLycopodiumalkaloid, is discussed. The mass spectra of luciduline and some of its derivatives are interpreted in terms of structure1.