Magnetic susceptibility shift selected imaging: MESSI.
Magnetic susceptibility shift selected imaging: MESSI.
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磁化率位移选择成像：MESSI。
DOI：
10.1002/mrm.1910160109
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发表时间：
1990
影响因子：
3.3
通讯作者：
SpringerJr,CS
中科院分区：
文献类型：
--
作者：
Xu,Y;Balschi,JA;SpringerJr,CS
顺磁性化合物通常用于增强MRI中的对比度，这是由于它们增加了水1H磁化弛豫的动力学。在这里，我们展示了一种对比度增强的方法，这是基于共振频率的位移所造成的散装磁化率（BMS）的影响，这样的化合物。这涉及在成像序列期间在没有场梯度的情况下对水1H共振的一部分进行频率选择性激励，该水1H共振的一部分仅通过BMS偏移而变得不均匀。产生的图像是样品的产生激发的光谱部分的那部分的图像。制备模拟组织的某些方面的体模样品，特别是在磁场中具有不同取向的血管。这里展示的对比度增强避免了使用顺磁试剂所带来的一些失真。原则上，这种新方法可以利用所有组织中发现的天然BMS差异。出版社：Academic Press，Inc.
Paramagnetic compounds are often used to enhance contrast in MRI by virtue of their increase in the kinetics of the relaxation of water1H magnetization. Here, we demonstrate a method for contrast enhancement which is based on the resonance frequency shifts caused by the bulk magnetic susceptibility (BMS) effects of such compounds. This involves the frequency selective excitation in the absence of field gradients, during the imaging sequence, of a portion of the water1H resonance which is rendered inhomogeneous by BMS shifts only. The image which results is of that portion of the sample which gives rise to the portion of the spectrum excited. A phantom sample which simulates some aspects of tissue, particularly blood vessels with different orientations in the magnetic field, was prepared. The contrast enhancement exhibited here avoids some of the distortions attendant to the use of paramagnetic reagents. This new approach can, in principle, utilize the natural BMS differences found in all tissue. © 1990 Academic Press, Inc.