Psychophysiologic assessment of mental imagery of stressful events in Israeli civilian posttraumatic stress disorder patients.
Psychophysiologic assessment of mental imagery of stressful events in Israeli civilian posttraumatic stress disorder patients.
复制标题
对以色列平民创伤后应激障碍患者应激事件心理意象的心理生理学评估。
DOI：
10.1016/s0010-440x(97)90059-6
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发表时间：
1997
影响因子：
7.3
通讯作者：
Pitman,RK
中科院分区：
文献类型：
--
作者：
Shalev,AY;Peri,T;Gelpin,E;Orr,SP;Pitman,RK
这项研究探讨了创伤后应激障碍（PTSD）患者对一个应激事件的生理反应，该事件发生在他们发病之前，与其病因无关：海湾战争的飞毛腿导弹警报。在先前的PTSD研究中使用了心理意象技术。每个受试者都要听三段30秒的录音带，包括（1）海湾战争的导弹警报，（2）恐怖袭击的无线电广播，（3）标准化的放松场景。受试者被指示尽可能生动地想象每个事件，同时测量心率（HR）、皮肤电导（SC）和左侧额肌肌电图（EMG）反应。将12例PTSD门诊患者的反应与惊恐障碍患者（n = 11）、未发生PTSD的创伤事件幸存者（n = 9）和无重大创伤终身史的精神健康受试者（n = 19）进行比较。多变量方差分析（MANOVA）的三个生理措施显示了显着的组间差异，在图像的海湾战争警报，与创伤后应激障碍的主题表现出较高的SC和EMG的反应比其他人。当年龄、战争期间的痛苦程度和并发的焦虑被控制时，差异仍然显着。对其他刺激的反应没有组间差异。我们的结论是，创伤后应激障碍患者可能会获得和维持长期的条件反应，各种压力在他们的生命周期或成为敏感的提醒过去的创伤后，他们的疾病发作。在易患PTSD的受试者中，在创伤前可能会表现出更高的条件性。
This study explored the physiological responses of posttraumatic stress disorder (PTSD) patients to reminders of a stressful event that had preceded the onset of their illness and was not related to its cause: the SCUD missile alarms of the Gulf War. A mental-imagery technique used in previous studies of PTSD was used. Three 30-second audiotapes were presented to each subject, including (1) the Gulf War's missile alarm, (2) a radio announcement of a terrorist attack, and (3) a standardized relaxing scene. Subjects were instructed to imagine each event as vividly as possible while heart rate (HR), skin conductance (SC), and left lateral frontalis electromyogram (EMG) responses were measured. The responses of 12 outpatients with PTSD were compared with those of panic disorder patients (n = 11), survivors of traumatic events who had not developed PTSD (n = 9), and mentally healthy subjects with no lifetime history of major trauma (n = 19). Multivariate analysis of variance (MANOVA) for the three physiological measures showed a significant group difference during imagery of the Gulf War alarm, with PTSD subjects showing higher SC and EMG responses than the others. The differences remained significant when age, level of distress during the war, and concurrent anxiety were controlled for. There were no group differences in responses to the other stimuli. We conclude that, PTSD patients may either acquire and maintain prolonged conditioned responses to various stressors during their life span or become sensitized to reminders of past traumata following the onset of their illness. Heightened conditionability may be expressed before the trauma in subjects who are liable to develop PTSD.