Effects of small medial preoptic area lesions on maternal behavior: Retreiving and nest building in the rat
Effects of small medial preoptic area lesions on maternal behavior: Retreiving and nest building in the rat
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DOI：
10.1016/0006-8993(80)91226-3
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发表时间：
1980-08
期刊：
影响因子：
2.9
通讯作者：
C. D. Jacobson;J. Terkel;R. Gorski;C. Sawyer
中科院分区：
文献类型：
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作者：
C. D. Jacobson;J. Terkel;R. Gorski;C. Sawyer
先前在大鼠中的研究表明，内侧视前区（MPOA）的大病变破坏了母性行为的各个方面。在本研究中，小的双边电解质病变的哺乳期女性的MPOA废除巢建设和检索组件的母亲的行为，而蹲下和护理不受影响。动物未能表现出检索和筑巢行为往往有更大的面积内的MPOA的背侧部分的病变。虽然背侧MPOA可能在维持母体行为的活跃成分（即筑巢和取巢）中发挥作用，但确定母体行为哪些成分被破坏的另一个关键因素可能是病变的大小。随着受损组织面积的增加，母体行为的组成部分也随之增加，这些组成部分被破坏。视前区性二形核的损伤与取巢和筑巢之间没有相关性。
Previous studies in rats have demonstrated that large lesions in the medial preoptic area (MPOA) disrupt all aspects of maternal behavior. In the present study, small bilateral electrolytic lesions in the MPOA of lactating females abolished nest building and retrieving components of maternal behavior while crouching and nursing were unaffected. Animals which failed to show retrieval and nest building behaviors tended to have a greater area of lesion within the more dorsal part of the MPOA. Although the dorsal MPOA may play a role in the maintenance of the active components of maternal behavior, i.e. nest building and retrieving, another critical factor in determining which components of maternal behavior are disrupted may be the size of the lesion. As one increases the area of damaged tissue there is also an accompanying increase in the components of maternal behavior which are disrupted. No correlation was found between damage to the Sexually Dimorphic Nucleus of the preoptic area and retrieving and nest building.