Coherence in children with Attention-Deficit/Hyperactivity Disorder and excess beta activity in their EEG
Coherence in children with Attention-Deficit/Hyperactivity Disorder and excess beta activity in their EEG
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DOI：
10.1016/j.clinph.2007.04.006
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发表时间：
2007-07-01
影响因子：
4.7
通讯作者：
Croft, Rodney J.
中科院分区：
文献类型：
--
作者：
Clarke, Adam R.;Barry, Robert J.;Croft, Rodney J.
目的：本研究探讨了两组儿童与注意缺陷多动障碍（ADHD）的连贯性措施之间的差异-与典型的脑电图轮廓（增加θ和β活动减少），并与过量的β活动-和正常对照group.Methods：34名儿童ADHD被列入每个典型和过量的β组，年龄和性别匹配的34个对照组。脑电图记录从21个网站在闭眼休息条件。波形的连贯性进行了计算，为8个半球内和8个半球间的电极对，三角洲，θ，α和β bands.Results：在比较的控制，典型的ADHD组主要有增加半球内θ和β的连贯性在短介质电极间的距离，并增加半球间的连贯性θ在额叶和中央/顶叶/枕叶区域。他们的半球间短-中电极间距离的偏侧效应在θ波段降低。过量β组和对照组之间的差异主要发现在偏侧的半球内θ相干在短-中电极距离，并增加半球间θ相干在额叶区域。减少三角洲的一致性在颞区也被发现。结论：这些结果表明，ADHD儿童与多余的β功率有一个潜在的大脑功能障碍，在额叶，这是常见的儿童与典型的脑电图配置文件。然而，一些定性的差异存在，这可能与其他方面的ADHD诊断或另一个comorbid condition.Significance：这是第一次研究，以探讨脑电的连贯性ADHD儿童谁增加了β功率。(c)2007年国际临床神经生理学联合会。由Elsevier爱尔兰有限公司出版。保留所有权利。
Objective: This study investigated differences in coherence measures between two groups of children with Attention-Deficit/Hyperactivity Disorder (ADHD) - with the typical EEG profile (increased theta and decreased beta activity), and with excess beta activity - and a normal control group.Methods: Thirty-four children with ADHD were included in each of the typical and excess beta groups, and were age and sex matched with 34 control subjects. EEG was recorded from 21 sites during an eyes-closed resting condition. Wave-shape coherence was calculated for eight intrahemi spheric and eight interhemispheric electrode pairs, for the, delta, theta, alpha and beta bands.Results: In comparison to the controls, the typical ADHD group primarily had increased intrahemispheric theta and beta coherence at short-medium inter-electrode distances, and increased interhemispheric coherence for theta in the frontal and central/parietal/occipital regions. Their laterality effect for interhemispheric short-medium inter-electrode distances was reduced in the theta band. Differences between the excess beta group and the control group were primarily found in laterality of the intrahemispheric theta coherence at short-medium electrode distances, and increased interhemispheric theta coherence in the frontal regions. Reduced delta coherence in the temporal regions was also found.Conclusions: These results suggest that ADHD children with excess beta power have an underlying brain dysfunction in the frontal lobes which is found in common with children with the typical EEG profile. However a number of qualitative differences exist which could be associated with other aspects of the ADHD diagnosis or another comorbid condition.Significance: This is the first study to investigate EEG coherence in ADHD children who have increased beta power. (c) 2007 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.