Contrast-transfer efficiency for continuously varying tissue moduli: Simulation and phantom validation
Contrast-transfer efficiency for continuously varying tissue moduli: Simulation and phantom validation
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DOI：
10.1016/s0301-5629(01)00411-2
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发表时间：
2001-08-01
影响因子：
2.9
通讯作者：
Ophir, J
中科院分区：
文献类型：
--
作者：
Kallel, F;Prihoda, CD;Ophir, J
本研究由两部分组成。在第一部分中，对弹性成像中的对比传递效率（CTE）进行了扩展，以考虑模量分布的连续变化。结果表明，对于有限尺寸的背景，在高斯分布情况下，应变对比接近模量对比。因此，获得了CTE的增加。当背景大小固定时，CTE随高斯分布SD的增大而增大。这种特性可以用夹杂物/背景界面处应变浓度的重新分布来解释。在研究的第二部分，对CTE进行了实验验证。制备了6种凝胶/琼脂/水基幻影包埋物，模量对比在+/- 6db之间。结果表明，界面夹杂物/背景处的模量是连续的，与已知的尖锐边界情况相比，这反过来导致CTE的增加。渗透压力梯度的存在可以解释连续的包体/背景界面。（E-mail: Faouzi.Kallel@uth.tme.edu） (C) 2001年世界超声医学和生物学联合会。
This study consisted of two parts. In the first part, the contrast-transfer efficiency (CTE) in elastography was extended to account for continuous changes of modulus distribution. It was shown that, for a finite size background, the strain contrast approaches the modulus contrast in the case of Gaussian distributions. Thus, an increase in the CTE was obtained. For a fixed background size, it was shown that the CTE increases as the SD of the Gaussian distribution increases. This property was explained by the redistribution of strain concentrations at the inclusion/background interface. In the second part of the study, the CTE was verified experimentally. Six gelatin/agar/water-based phantoms embedding inclusions with modulus contrast varying between +/- 6 dB were manufactured. It was shown that the modulus at the interface inclusion/background was continuous and, in turn, resulted in an increase of the CTE as compared to the known case of a sharp boundary. The continuous inclusion/background interface was explained by the existence of an osmotic pressure gradient. (E-mail: Faouzi.Kallel@uth.tme.edu) (C) 2001 World Federation for Ultrasound in Medicine & Biology.