Characterization of Streptococcus pyogenes isolated from balanoposthitis patients presumably transmitted by penile-oral sexual intercourse

Characterization of Streptococcus pyogenes isolated from balanoposthitis patients presumably transmitted by penile-oral sexual intercourse
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从可能通过阴茎口性交传播的龟头包皮炎患者中分离出的化脓性链球菌的特征

DOI:
10.1007/s00284-010-9581-x
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发表时间:
2010
期刊:
影响因子:
2.6
通讯作者:
Hasegawa T
Hasegawa T
中科院分区:
生物学4区
文献类型:
--
作者:
Minami M;Wakimoto Y;Matsumoto M;Matsui H;Kubota Y;Okada A;Isaka M;Tatsuno I;Tanaka Y;Hasegawa T

文献摘要

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原产于人类咽部的化脓链球菌,可引起急性咽炎。阴道炎是龟头和包皮的炎症性疾病。然而,由ys引起的平衡骨炎。化脓不被广泛认为是一种性传播疾病。此外,引起balanopthitis的分离株的细菌学特征尚不清楚。四。对成人balanposthitis中分离的化脓性菌株进行了检测。我们对链球菌热原外毒素相关基因和耐药基因进行了分型、T抗原分型、RAPD、PCR检测和药敏试验。4株菌株均怀疑为经阴茎-口腔性交传播,经遗传分析发现菌株存在差异,并存在一定的耐药因子。我们建议这样做。化脓性应被认为是性传播疾病的一种病原体。抗药性。当balanposthitis患者使用抗生素治疗时,必须考虑到化脓性。
Streptococcuspyogenesis indigenous to the human pharynx and causes acute pharyngitis. Balanoposthitis is an inflammatory disease of the glans and the foreskin. However, balanoposthitis caused byS.pyogenesis not widely recognized as a sexually transmitted disease. In addition, bacteriological features of the isolates causing balanoposthitis are unclear. The fourS.pyogenesstrains isolated from adult balanoposthitis were examined. We performedemmtyping, T antigen typing, RAPD assay, PCR assay for the streptococcal pyrogenic exotoxin-related genes and antibiotic-resistant genes, and antibiotic susceptibility assay. All four strains were suspected to be transmitted by penile-oral sexual intercourse, were found to be different by genetic analysis, and also harbored some antibiotic-resistant factors. We propose thatS.pyogenesshould be considered as a causative agent of sexually transmitted disease. The drug resistantS.pyogenesmust be taken into account when balanoposthitis patients are treated with antibiotic.