Measurement of 3D refractive index distribution by optical diffraction tomography
Measurement of 3D refractive index distribution by optical diffraction tomography
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DOI：
10.1117/12.2296310
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发表时间：
2018-01
期刊：
影响因子：
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通讯作者：
Weining Chi;Dayong Wang;Yunxin Wang;Jie Zhao;L. Rong;Yu Yuan
中科院分区：
文献类型：
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作者：
Weining Chi;Dayong Wang;Yunxin Wang;Jie Zhao;L. Rong;Yu Yuan
光学衍射层析成像技术（Optical Diffraction Tomography，ODT）作为一种新型的三维成像技术，可以获得透明样品的三维折射率分布，从而揭示透明样品的重要光学性质。根据光学衍射层析成像原理，建立了基于马赫-曾德尔干涉仪的光学衍射层析成像系统。利用二维平移台控制物光的传播方向，用电荷耦合器件（CCD）记录了121幅不同照明角度的全息图。为了验证该方法的有效性和准确性，首先测量了折射率已知的微球的三维折射率分布。采用迭代约束算法，有效地提高了成像精度。微球的三维形貌和平均RI与实际情况一致，RI误差小于0.0033。然后，以激光加工的折射率不均匀的光学元件为样品。利用光学衍射层析成像系统获得了其三维折射率分布。
Optical Diffraction Tomography (ODT), as a novel 3D imaging technique, can obtain a 3D refractive index (RI) distribution to reveal the important optical properties of transparent samples. According to the theory of ODT, an optical diffraction tomography setup is built based on the Mach-Zehnder interferometer. The propagation direction of object beam is controlled by a 2D translation stage, and 121 holograms based on different illumination angles are recorded by a Charge-coupled Device (CCD). In order to prove the validity and accuracy of the ODT, the 3D RI profile of microsphere with a known RI is firstly measured. An iterative constraint algorithm is employed to improve the imaging accuracy effectively. The 3D morphology and average RI of the microsphere are consistent with that of the actual situation, and the RI error is less than 0.0033. Then, an optical element fabricated by laser with a non-uniform RI is taken as the sample. Its 3D RI profile is obtained by the optical diffraction tomography system.