Unmasking Nonpreserved Heart Structure, Function, and Energetics in Heart Failure With Preserved Ejection Fraction With Magnetic Resonance Imaging Coupled With Exercise.
Unmasking Nonpreserved Heart Structure, Function, and Energetics in Heart Failure With Preserved Ejection Fraction With Magnetic Resonance Imaging Coupled With Exercise.
复制标题
通过磁共振成像结合运动，揭示保留射血分数的心力衰竭中未保留的心脏结构、功能和能量。
DOI：
10.1161/circulationaha.121.056974
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发表时间：
2021
期刊：
影响因子：
37.8
通讯作者：
Lewis,GregoryD
中科院分区：
文献类型：
--
作者：
Ho,JenniferE;Nguyen,Christopher;Lewis,GregoryD
有保留射血分数的心力衰竭（HFpEF）以前已被定义为各种标准，其中一个共同的主题是存在保留左心室射血分数。在心脏正常的基础上定义心脏病应该引出一个问题：HFpEF的心脏有什么明显的异常？回答这个问题可能有助于克服迄今为止用药理学方法治疗HFpEF的有限成功的记录。
Heart failure with preserved ejection fraction (HFpEF) has been previously defined by various criteria, 1 with a common theme being the presence of preserved left ventricular ejection fraction. Defining a heart disease on the basis of a normal cardiac finding should beg the question: What is distinctly abnormal about the heart in HFpEF? Answering this question may aid in overcoming a track record of limited success to date with pharmacological approaches to HFpEF.