Large-scale characterization of introns in the Pneumocystis carinii genome.
Large-scale characterization of introns in the Pneumocystis carinii genome.
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卡氏肺囊虫基因组内含子的大规模表征。
DOI：
10.1111/j.1550-7408.2006.00211.x
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发表时间：
2006
期刊：
影响因子：
--
通讯作者：
Meller,Jaroslaw
中科院分区：
文献类型：
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作者：
Slaven,BradleyE;Porollo,Aleksey;Sesterhenn,Thomas;Smulian,AGeorge;Cushion,MelanieT;Meller,Jaroslaw
本文介绍了一项研究，利用从肺囊虫基因组计划获得的基因组和转录序列数据，对卡氏肺囊虫内含子进行大规模表征。通过统计分析，确定了供体、受体和分支位点模式，以及内含子、外显子和总体A+ T碱基对含量。这一策略将有助于提高卡氏肺囊虫基因鉴定和新基因发现的准确性。
The article presents a study that conducts a large-scale characterization of Pneumocystis carinii introns using genomic and transcriptional sequence data obtained from the Pneumocystis Genome Project. Using statistical analysis, donor, acceptor and branch site patterns, as well as intron, exon, and overall A+ T base pair content were identified. This strategy should lead to improvement in the accuracy in identifying Pneumocystis carinii genes and finding novel genes.