Optimization and Evaluation of a Vascular Coupling Device for End-to-End Anastomosis: A Finite-Element Analysis
Optimization and Evaluation of a Vascular Coupling Device for End-to-End Anastomosis: A Finite-Element Analysis
复制标题
DOI：
10.1115/1.4031810
复制
发表时间：
2016-03-01
影响因子：
0.9
通讯作者：
Gale, Bruce K.
中科院分区：
文献类型：
--
作者：
Li, Huizhong;Agarwal, Jay;Gale, Bruce K.
目前，血管的端对端吻合是通过缝合来进行的，这种方法耗时、昂贵并且存在很大程度的人为错误。一种有前途的替代方案是环销耦合装置。该装置已被证明可用于静脉吻合，但缺乏动脉应用所需的多功能性。本研究的目的是优化可用于各种尺寸的动脉和静脉的血管耦合设计。为了实现这一目标，使用有限元 (FE) 分析来模拟吻合过程中血管与器械的相互作用。进行参数模拟以优化设计的销数量、机翼枢轴点和销偏移。还评估了耦合器与各种血管尺寸的相互作用。血管壁的最大应变随着针的数量而增加。翼和销的位置对于决定最大应变也很重要，尺寸不当会导致安装过程失败。在耦合器安装过程中，需要向容器远端施加额外的力或辅助工具，以防止内径小于 3 毫米（壁厚 0.5 毫米）的容器从耦合器上滑落。
Currently, end-to-end anastomosis of blood vessels is performed using suturing, which is time consuming, expensive, and subject to large degrees of human error. One promising alternative is a ring-pin coupling device. This device has been shown to be useful for venous anastomosis, but lacks the versatility necessary for arterial applications. The purpose of this study was to optimize a vascular coupling design that could be used for arteries and veins of various sizes. To achieve this, finite-element (FE) analysis was used to simulate the vessel-device interaction during anastomosis. Parametric simulations were performed to optimize the number of pins, the wing pivot point, and the pin offset of the design. The interaction of the coupler with various blood vessel sizes was also evaluated. Maximum strain in the vessel wall increased with the number of pins. The positions of the wings and pins were also important in dictating maximum strain, and improper dimensions lead to failure of the installation process. Extra force applied to the distal end of the vessel, or a supplementary tool, will be required during the coupler installation process to prevent vessels less than 3 mm inner diameter (0.5 mm wall thickness) from slipping off the coupler.