Adaptation of cells derived from human malignant tumours to growth in vitro.
Adaptation of cells derived from human malignant tumours to growth in vitro.
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源自人类恶性肿瘤的细胞适应体外生长。
DOI：
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发表时间：
1976
期刊：
影响因子：
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通讯作者：
Gear Jh
中科院分区：
文献类型：
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作者：
Alexander Jj;E. Bey;Whitcutt Jm;Gear Jh
在体外培养了45例人类恶性肿瘤标本，试图确定肿瘤细胞维持的必要条件，并建立永久生长的细胞系。连续生长的培养物来自五种肿瘤，包括食道癌和结肠癌、肝癌、间皮瘤和腹膜后肉瘤。食道癌和肝癌已完全适应体外条件，可视为已建立的细胞系。
Forty-five human malignant tumour specimens were cultivated in vitro in an attempt to determine the necessary conditions for tumour cell maintenance and to establish permanently-growing cell lines. Continuously-growing cultures were derived from five tumours, including carcinomas of the oesophagus and colon, a hepatoma, a mesothelioma and a retroperitoneal sarcoma. The carcinoma of the oesophagus and the hepatoma, which have adapted fully to in vitro conditions, can be regarded as established cell lines.