Atypical acquisition and atypical expression of memory consolidation gains in a motor skill in young female adults with ADHD
Atypical acquisition and atypical expression of memory consolidation gains in a motor skill in young female adults with ADHD
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DOI：
10.1016/j.ridd.2011.01.048
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发表时间：
2011-05-01
影响因子：
3.1
通讯作者：
Karni, Avi
中科院分区：
文献类型：
--
作者：
Adi-Japha, Esther;Fox, Orly;Karni, Avi
患有多动症的人经常表现出运动任务的表现缺陷。然而，尚不清楚这是否反映了多动症患者技能（程序性知识）获取效率较低，或者长期记忆巩固不足。该研究的目的是比较患有和不患有多动症的人熟练运动表现的获得、延迟巩固阶段的表达——增益和保留。 32 名参与者（其中 16 名患有多动症）使用完善的训练方案接受了一系列手指运动的训练，并在训练前以及训练后立即、24 小时和 2 周进行了测试。两组在训练中的速度增益相似；此外，延迟增益在 24 小时和训练后 2 周表达，但在 ADHD 中表现较差。然而，虽然对照显示训练后 24 小时和 2 周的准确度显着延迟增长，但 ADHD 的准确度从训练前到训练后 24 小时下降，并且在训练后 2 周时仅恢复到训练前的水平。我们的结果表明，患有多动症的个体在运动序列学习中存在潜在的记忆巩固阶段，表现为速度的延迟增长和训练前准确性的恢复大大延迟。然而，运动技能的习得和记忆巩固在多动症中都是不典型的。 (C) 2011 Elsevier Ltd. 保留所有权利。
Individuals with ADHD often show performance deficits in motor tasks. It is not clear, however, whether this reflects less effective acquisition of skill (procedural knowledge), or deficient consolidation into long-term memory, in ADHD. The aim of the study was to compare the acquisition of skilled motor performance, the expression of delayed consolidation phase - gains and retention, in persons with and without ADHD. Thirty-two participants, 16 with ADHD, were trained on a sequence of finger movements using a well-established training protocol, and tested before training and immediately, 24 h and 2 weeks after training. Both groups showed similar within-session gains in speed; additional, delayed gains were expressed at 24 h, but less robustly in ADHD, and at 2 weeks post-training. However, while controls showed significant delayed gains in accuracy at 24 h and 2 weeks post-training, accuracy deteriorated in ADHD from pre-training to 24 h post-training and was only at pre-training levels by 2-weeks post-training. Our results demonstrate a latent memory consolidation phase in motor sequence learning, expressed as delayed gains in speed and a much delayed recovery of pre-training accuracy, in individuals with ADHD. However, both the acquisition and memory consolidation of motor skills are atypical in ADHD. (C) 2011 Elsevier Ltd. All rights reserved.