The temporal relationship between speech auditory brainstem responses and the acoustic pattern of the phoneme |ba| in normal-hearing adults
The temporal relationship between speech auditory brainstem responses and the acoustic pattern of the phoneme |ba| in normal-hearing adults
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DOI：
10.1016/j.clinph.2007.12.010
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发表时间：
2008-04-01
影响因子：
4.7
通讯作者：
Thai-Van, H.
中科院分区：
文献类型：
--
作者：
Akhoun, I.;Gallego, S.;Thai-Van, H.
目的：探讨语音-听觉脑干反应与ba/音素声学模式的时间关系。方法：记录23例正常听力受试者对/ba/的言语诱发性听觉脑干反应（Speech ABR）。研究了刺激强度对11例被试言语ABR成分潜伏期的影响。测量了不同换能器对电磁泄漏的影响。结果：言语ABR在刺激开始后6 ms出现可重复的启动反应（OR）。频率跟随响应（FFR）波形模拟了500 Hz低通滤波音素/ba/的时间波形，延迟位移为14.6 ms。此外，OR和FFR潜伏期随刺激强度的增加而降低，其中FFR潜伏期（-1.4 ms/10 dB）高于OR潜伏期（-0.6 ms/10 dB）。结论：声刺激模式与FFR颞叶结构有密切关系。此外，延迟行为的差异表明FFR和OR的产生机制不同。意义：研究结果进一步揭示了人类脑干水平上基本言语刺激的时间编码。(c) 2007年国际临床神经生理学联合会。爱思唯尔爱尔兰有限公司出版。版权所有。
Objective: To investigate the temporal relationship between speech auditory brainstem responses and acoustic pattern of the phoneme ba/.Methods: Speech elicited auditory brainstem responses (Speech ABR) to /ba/ were recorded in 23 normal-hearing subjects. Effect of stimulus intensity was assessed on Speech ABR components latencies in 11 subjects. The effect of different transducers on electromagnetic leakage was also measured.Results: Speech ABR showed a reproducible onset response (OR) 6 ms after stimulus onset. The frequency following response (FFR) waveform mimicked the 500 Hz low pass filtered temporal waveform of phoneme /ba/ with a latency shift of 14.6 ms. In addition, the OR and FFR latencies decreased with increasing stimulus intensity, with a greater rate for FFR (-1.4 ms/10 dB) than for OR (-0.6 ms/10 dB).Conclusions: A close relationship was found between the pattern of the acoustic stimulus and the FFR temporal structure. Furthermore, differences in latency behaviour suggest different generation mechanisms for FFR and OR.Significance: The results provided further insight into the temporal encoding of basic speech stimulus at the brainstem level in humans. (c) 2007 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.