Accommodation of the human lens capsule using a finite element model based on nonlinear regionally anisotropic biomembranes
Accommodation of the human lens capsule using a finite element model based on nonlinear regionally anisotropic biomembranes
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DOI：
10.1080/10255842.2016.1228907
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发表时间：
2017-01-01
影响因子：
1.6
通讯作者：
Humphrey, J. D.
中科院分区：
文献类型：
--
作者：
David, G.;Pedrigi, R. M.;Humphrey, J. D.
眼睛的调节机制，即允许人类将视线聚焦在近距离物体上的机制，会随着年龄的增长而自然减弱，形成老花眼。接受白内障手术的人，使用目前的手术方法和人工晶状体植入，也没有适应能力。迁就的过程通常是众所周知的；然而，由于进行体内研究的困难和后果，具体的机械细节尚未得到充分解释。大多数研究在线性弹性、各向同性、均匀透镜和透镜囊的假设下模拟了调节力学。最近的实验和数值研究表明，晶状体包膜具有非线性弹性和区域各向异性。在本文中，我们提出了一个数值模型的人类住宿使用基于膜理论的有限元方法，结合最近发现的荚膜性质。本研究旨在为住宿机制提供一种新的视角。这些发现可能在寻找生物医学解决方案以恢复视力丧失方面具有重要意义。
Accommodation of the eyes, the mechanism that allows humans to focus their vision on near objects, naturally diminishes with age via presbyopia. People who have undergone cataract surgery, using current surgical methods and artificial lens implants, are also left without the ability to accommodate. The process of accommodation is generally well known; however the specific mechanical details have not been adequately explained due to difficulties and consequences of performing in vivo studies. Most studies have modeled the mechanics of accommodation under assumptions of a linearly elastic, isotropic, homogenous lens and lens capsule. Recent experimental and numerical studies showed that the lens capsule exhibits nonlinear elasticity and regional anisotropy. In this paper we present a numerical model of human accommodation using a membrane theory based finite element approach, incorporating recent findings on capsular properties. This study seeks to provide a novel perspective of the mechanics of accommodation. Such findings may prove significant in seeking biomedical solutions to restoring loss of visual power.