SURFACTIN ITURIN-A INTERACTIONS MAY EXPLAIN THE SYNERGISTIC EFFECT OF SURFACTIN ON THE BIOLOGICAL PROPERTIES OF ITURIN-A
SURFACTIN ITURIN-A INTERACTIONS MAY EXPLAIN THE SYNERGISTIC EFFECT OF SURFACTIN ON THE BIOLOGICAL PROPERTIES OF ITURIN-A
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DOI：
10.1016/0300-9084(92)90002-v
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发表时间：
1992-12-01
期刊：
影响因子：
3.9
通讯作者：
PTAK, M
中科院分区：
文献类型：
--
作者：
MAGETDANA, R;THIMON, L;PTAK, M
Iturin A和surfactin是从同一株枯草芽孢杆菌中提取的两种脂肽。伊图里蛋白A具有抗菌和抗真菌活性，表面活性素是一种强表面活性剂。表面活性素的存在，在其单独无活性的浓度下，在很大程度上增加了伊枯草菌素A诱导的溶血百分比。这种协同效应似乎与伊枯草菌素A和表面活性素之间的相互作用有关。伊图里蛋白A吸附并渗透到表面活性素单层中。伊图里蛋白A和表面活性素是可混溶的，并且在混合单层中特异性地相互作用。
Iturin A and surfactin are two lipopeptides extracted from a same strain of Bacillus subtilis. Iturin A possesses antibiotic and antifungal activities and surfactin is a strong surfactant. The presence of surfactin, at a concentration at which, alone, it is inactive, increases to a very large extent the haemolysis percent induced by iturin A. This synergistic effect seems to be in relation with interactions between iturin A and surfactin. Iturin A adsorbs to and penetrates into surfactin monolayers. Iturin A and surfactin are miscible and interact specifically in mixed monolayers.