Prospects of IL-2 in Cancer Immunotherapy.
Prospects of IL-2 in Cancer Immunotherapy.
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DOI:
10.1155/2018/9056173
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发表时间:
2018
影响因子:
--
通讯作者:
Jamal MS
中科院分区:
文献类型:
--
作者:
Choudhry H;Helmi N;Abdulaal WH;Zeyadi M;Zamzami MA;Wu W;Mahmoud MM;Warsi MK;Rasool M;Jamal MS
IL-2 is a powerful immune growth factor and it plays important role in sustaining T cell response. The potential of IL-2 in expanding T cells without loss of functionality has led to its early use in cancer immunotherapy. IL-2 has been reported to induce complete and durable regressions in cancer patients but immune related adverse effects have been reported (irAE). The present review discusses the prospects of IL-2 in immunotherapy for cancer.
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