Antioxidative activity of the blue pigment formed in a D-xylose-glycine reaction system
Antioxidative activity of the blue pigment formed in a D-xylose-glycine reaction system
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DOI：
10.1271/bbb.67.54
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发表时间：
2003-01-01
影响因子：
1.6
通讯作者：
Hayase, F
中科院分区：
文献类型：
--
作者：
Shizuuchi, S;Hayase, F
由 1 M D-木糖和 0.1 M 甘氨酸制备蓝色化合物，并命名为 Blue-M1，是类黑素的中间颜色产物。众所周知，蛋白黑素具有抗氧化活性以及对活性氧的高清除活性，因此除了 Blue-M1 对羟基和 DPPH 自由基的清除活性外，还研究了 Blue-M1 对亚油酸过氧化的抗氧化活性。Blue-M1 与蛋白黑素一样有效地抑制了亚油酸的过氧化。 Blue-M1 对羟基和 DPPH 自由基的清除活性也与类黑素一样强。 Blue-M1 随着浓度的增加表现出更高的活性。 Blue-M1 中的吡咯并吡咯环和两个吡咯并吡咯环之间的次甲基桥可能与自由基清除活性的能力有关，但与四个羧基无关。
A blue compound was prepared from 1 M D-xylose and 0.1 M glycine, and designated Blue-M1, an intermediate color product of melanoidins. As melanoidins are well known to have antioxidative activity as well as high scavenging activity against active oxygen species, the antioxidative activity of Blue-M1 against the peroxidation of linoleic acid was investigated, in addition to the scavenging activity of Blue-M1 toward hydroxyl and DPPH radicals.Blue-M1 suppressed the peroxidation of linoleic acid as effectively as melanoidins did. The scavenging activity of Blue-M1 toward hydroxyl and DPPH radicals was also as strong as that of melanoidins. Blue-M1 showed higher activity with increasing concentration. The pyrrolopyrrole ring and a methine bridge between two pyrrolopyrrole rings in Blue-M1 could be related to the ability for radical scavenging activity, but not four carboxyl groups.