A Non Invasive Wearable Sensor for the Measurement of Brain Temperature
A Non Invasive Wearable Sensor for the Measurement of Brain Temperature
复制标题
DOI：
10.1109/iembs.2006.259429
复制
发表时间：
2006
期刊：
影响因子：
--
通讯作者：
A. Dittmar;C. Géhin;G. Delhomme;D. Boivin;G. Dumont;Christopher Mott
中科院分区：
文献类型：
--
作者：
A. Dittmar;C. Géhin;G. Delhomme;D. Boivin;G. Dumont;Christopher Mott
由于体温调节中心位于大脑深处，因此大脑温度是体温、生理节律和精神活动最重要的标志之一。然而，由于缺乏可及性，大脑温度不容易测量。腋窝、颊部、鼓室和直肠的温度不能完全反映大脑的温度。然而，直肠温度可能是最可靠的核心体温指标。脑温度可以用核磁共振光谱、微波辐射测量、近红外光谱、超声波测温来测量。然而，这些方法都不适合在实验室或医院以外的日常活动、运动等期间长期门诊使用。由法国里昂理工学院LPM生物医学微传感器部门开发的脑核心温度传感器是一种利用“零热流”原理的柔性有源传感器。该传感器已被用于实验测量：心理活动时的大脑温度，以及在医院用于昼夜节律的研究。结果与直肠探头测量结果一致。这种传感器有两种版本：一种是供医院使用的非门诊版本，一种是使用远程传输的门诊版本。我们正在努力提高动态版本的自主性，最多可达几天。这种可穿戴生物医学传感器（WBS）可用于时间生物学研究和医学治疗的昼夜节律评估
As the thermoregulation centres are deep in the brain, the cerebral temperature is one of the most important markers of fever, circadian rhythms physical and mental activities. However due to a lack of accessibility, the brain temperature is not easily measured. The axillary, buccal, tympanic and rectal temperatures do not reflect exactly the cerebral temperature. Nevertheless the rectal temperature is used as probably the most reliable indicator of the core body temperature. The brain temperature can be measured using NMR spectroscopy, microwave radiometry, near infrared spectroscopy, ultra-sound thermometry. However none of those methods are amenable to long term ambulatory use outside of the laboratory or of the hospital during normal daily activities, sport, etc. The brain core temperature "BCT" sensor, developed by the Biomedical Microsensors dpt of LPM at INSA-Lyon is a flexible active sensor using "zero-heat-flow" principle. The sensor has been used for experimental measurement: brain temperature during mental activity, and in hospital for the study of circadian rhythms. The results are in agreement with the measurement by the rectal probe. There are 2 versions of this sensor: a non ambulatory for the use in hospitals, and an ambulatory version using teletransmission. We are working for improving the autonomy of the ambulatory version up to several days. This wearable biomedical sensor (WBS) can be used for circadian assessment for chronobiology studies and in medical therapies