THE CULTURE OF DERMAL PAPILLA CELLS FROM HUMAN-HAIR FOLLICLES

THE CULTURE OF DERMAL PAPILLA CELLS FROM HUMAN-HAIR FOLLICLES
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DOI:
10.1111/j.1365-2133.1984.tb04705.x
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发表时间:
1984-01-01
影响因子:
10.3
通讯作者:
MESSENGER, AG
MESSENGER, AG
中科院分区:
医学1区
文献类型:
--
作者:
MESSENGER, AG

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从人毛囊中分离毛乳头,并从乳头外植体建立原代细胞培养物。培养的乳头细胞缓慢扩散,最初为单层,最终形成成纤维细胞样细胞的多层平行阵列。在扩张集落的边缘,细胞大而扁平,并显示出形成团块的趋势。人毛乳头细胞在培养中的行为与大鼠触须毛囊毛乳头细胞培养中报道的行为非常相似。
Dermal papillae were isolated from human hair follicles and primary cell cultures were established from the papilla explants. The cultured papilla cells spread slowly, initially as a monolayer, and eventually formed multi-layered parallel arrays of fibroblast-like cells. At the edges of expanding colonies the cells were large and flattened, and showed a tendency to form clumps. The behavior of human dermal papilla cells in culture is very similar to that reported in cultures of papilla cells from rat vibrissa follicles.