Wool keratin: a novel building block for layer-by-layer self-assembly.

Wool keratin: a novel building block for layer-by-layer self-assembly.
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DOI:
10.1016/j.jcis.2009.04.050
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发表时间:
2009-08
影响因子:
9.9
通讯作者:
Xiao Yang;Hui Zhang;Xiaoliang Yuan;Shuxun Cui
Xiao Yang;Hui Zhang;Xiaoliang Yuan;Shuxun Cui
中科院分区:
化学1区
文献类型:
--
作者:
Xiao Yang;Hui Zhang;Xiaoliang Yuan;Shuxun Cui

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我们利用提取的水溶性羊毛角蛋白作为逐层(LbL)组装的构建块。通过调节溶液pH,角蛋白可以作为聚阳离子或聚阴离子使用。实验结果表明,角蛋白与其他合成聚电解质的多层膜已经成功地制备。我们已经发现,含角蛋白的膜的每个双层的平均厚度明显大于以前报道的通常的多层膜。这一特性有助于在较少的沉积周期内制备相对较厚的薄膜。角蛋白在LbL组装中的使用有助于制备用于组织工程的生物相容性表面。
We utilize the extracted water-soluble wool keratin as the building block for the layer-by-layer (LbL) assembly. By adjusting the solution pH, keratin can be used as polycation or polyanion. Experimental results indicate that multilayer films of keratin together with other synthetic polyelectrolytes have been fabricated successfully. We have found that the average thickness of each bilayer of the keratin containing film is evidently larger than that of usual multilayer films previously reported. This feature is helpful to fabricate relatively thick films in less deposition cycles. The use of keratin in LbL assembly is helpful to prepare a biocompatible surface for tissue engineering.