BONE-DENSITY OF THE RADIUS, SPINE, AND HIP IN RELATION TO PERCENT OF IDEAL BODY-WEIGHT IN POSTMENOPAUSAL WOMEN
BONE-DENSITY OF THE RADIUS, SPINE, AND HIP IN RELATION TO PERCENT OF IDEAL BODY-WEIGHT IN POSTMENOPAUSAL WOMEN
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DOI：
10.1007/bf02556691
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发表时间：
1987-06-01
影响因子：
4.2
通讯作者：
DALLAL, G
中科院分区：
文献类型：
--
作者：
DAWSONHUGHES, B;SHIPP, C;DALLAL, G
采用双光子骨密度仪（DPA）和单光子骨密度仪（SPA）分别测定了40-70岁健康绝经后妇女腰椎（L2 ~ L4）和髋部（股骨颈、Ward's三角和大转子部位）的骨矿含量（BMC）和骨密度（BMD）。本文对97名理想体重（IBW）以上妇女和128名IBW以下妇女的BMC和BMD与绝经年限的关系进行了研究。较重的妇女在每个部位的平均BMC和BMD明显高于正常体重的妇女。在正常体重妇女中，除大转子外，各测量部位的BMD与绝经年限均呈显著负相关。在肥胖妇女中，仅桡骨部位的BMD随着绝经后年限的增加而降低，而髋部（股骨颈和Ward's三角区）以及桡骨的BMC随着绝经后年限的增加而降低。因此，在该人群中，体型是BMD的重要决定因素。Ward's三角区和股骨颈区的骨密度丢失模式与脊柱相似。在髋关节的BMC和BMD结果表明，重塑发生在这个承重部位，这对骨强度有有利的影响。
Bone mineral content (BMC) and bone mineral density (BMD) of the spine (L2-L4) and hip (at femoral neck, Ward''s triangle, and greater trochanter sites) were determined by dual-photon absorptiometry (DPA), and of the radius by single-photon absorptiometry (SPA) in healthy postmenopausal women aged 40-70 years. The relationships of BMC and BMD to years since menopause were examined separately in 97 women who were above 115% of ideal body weight (IBW) and in 128 women below. The heavier women had significantly greater mean BMC and BMD at each site than did the normal-weight women. In the normal-weight women, there was a significantly negative correlation between BMD and years since menopause at each measurement site except the greater trochanter. In the obese women, BMD decreased with increasing years since menopause at the radius site only and BMC declined with increasing years after menopause at the hip (femoral neck and Ward''s triangle region) as well as the radius. Thus, body size is a significant determinant of BMD in this population. The pattern of loss of BMD from Ward''s triangle and femoral neck regions of hip are similar to that of the spine. The BMC and BMD findings in the hip suggest that remodeling occurs at this weight-bearing site which has a favorable effect on bone strength.