Fibroids, infertility and pregnancy wastage
Fibroids, infertility and pregnancy wastage
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DOI：
10.1093/humupd/6.6.614
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发表时间：
2000-11-01
影响因子：
13.3
通讯作者：
Li, TC
中科院分区：
文献类型：
--
作者：
Bajekal, N;Li, TC
子宫肌瘤常见于育龄妇女。不同类型的肌瘤可能在不同程度上影响生殖结果，粘膜下肌瘤、肌壁内肌瘤和浆膜下肌瘤（按重要性降序排列）是不孕和流产的原因，肌瘤还可能在怀孕期间产生许多并发症，应建议计划接受辅助受孕的女性在 IVF 之前切除粘膜下肌瘤和可能的肌壁内肌瘤，无论其位置如何，都应考虑大肌瘤（> 5 cm）就个体而言，生殖史是一个重要的考虑因素。子宫肌瘤切除术后流产率显着降低，当存在较大的浆膜下或肌壁间肌瘤、多发性肌瘤或预计会进入子宫腔时，应选择开放式子宫肌瘤切除术。正确评估手术的益处和风险：在提供手术之前，应仔细考虑对个体患者进行手术的好处和风险。
Uterine fibroids are often found in women of reproductive age. Different types of fibroids may affect reproductive outcome to a different extent, with submucous, intramural and subserosal fibroids being (in decreasing order of importance) a cause of infertility and pregnancy wastage, Fibroids may also produce a number of complications during pregnancy, Women who are scheduled for assisted conception should be advised to have submucous and possibly intramural fibroids removed prior to IVF, Large fibroids (>5 cm), wherever their location, should be considered individually, with the reproductive history being an important consideration. Miscarriage rates are significantly reduced following myomectomy, Open myomectomy should be the route of choice when there are large subserosal or intramural fibroids, multiple fibroids or entry into the uterine cavity is to be expected. Proper assessment of the benefits and risks: of surgery for individual patients should be carefully considered before offering a procedure.