MECHANISM OF RESISTANCE TO INSECTICIDE IN HOUSEFLIES
MECHANISM OF RESISTANCE TO INSECTICIDE IN HOUSEFLIES
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DOI：
10.1038/168193a0
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发表时间：
1951-01-01
期刊：
影响因子：
64.8
通讯作者：
BUSVINE, JR
中科院分区：
文献类型：
--
作者：
BUSVINE, JR
将DDT滴入油中（丙酮挥发性太强），在外部或注射时也会产生类似的结果;因此，抵抗力不是由于角质层。撒丁岛耐药菌株是相对较低的耐药性比意大利耐药菌株的类似物的滴滴涕，如甲氧基滴滴涕是稳定的脱氯化氢在体外，这两种菌株是耐不稳定的类似物。在残留DDT的击倒试验中，意大利菌株具有抵抗力;撒丁岛苍蝇很快就瘫痪了，但在从薄膜中取出后恢复了。意大利株对DDT和除虫菊酯有抗性，对其他7种杀虫剂无抗性。撒丁岛菌株对DDT和其他5种（包括3种未在撒丁岛使用的菌株）具有抗性，但对除虫菊酯没有抗性。脱氯化氢可以解释撒丁岛菌株的耐药性，但意大利菌株必须假设另一种机制。
Minute drops of DDT in oil (acetone is too volatile) gave similar results externally or injected; thus, resistance is not due to the cuticle. The Sardinian resistant strain was relatively less resistant than the Italian resistant strain to analogs of DDT like methyoxychlor which are stable to dehydrochlorination in vitro; both strains were resistant to the labile analogs. In knock-down tests with residual DDT the Italian strain was resistant; the Sardinian flies were quickly paralyzed, but recovered after removal from the film. The Italian strain was resistant to DDT and pyrethrins, but not to 7 other insecticides. The Sardinian strain was resistant to DDT and 5 others (including 3 not used in Sardinia) but not to pyrethrins. Dehydrochlorination may account for resistance in the Sardinian strain, but another mechanism must be postulated for the Italian strain.