Two-phase helical CT for pancreatic tumors: Pancreatic versus hepatic phase enhancement of tumor, pancreas, and vascular structures
Two-phase helical CT for pancreatic tumors: Pancreatic versus hepatic phase enhancement of tumor, pancreas, and vascular structures
复制标题
DOI：
10.1148/radiology.199.3.8637990
复制
发表时间：
1996-06-01
期刊：
影响因子：
19.7
通讯作者：
Reber, HA
中科院分区：
文献类型：
--
作者：
Lu, DSK;Vedantham, S;Reber, HA
目的：定量评价和验证螺旋CT双期扫描技术在胰腺肿瘤诊断中的价值。材料与方法：27例经手术病理证实的胰腺癌患者，行螺旋CT双期扫描，扫描时间分别为胰腺期(静脉注射造影剂3mL/s后40~70s)和肝期(注射后70~100s)。结果：胰腺期肿瘤-胰腺平均对比度(67HU+/-19)明显大于肝期(39HU+/-16)(P<；.001)。这既是正常胰腺增强程度较高，也是胰腺期肿瘤增强程度较低的结果。包括门静脉在内的所有血管结构在胰腺期的不混浊程度也更高(P<；.001)。结论：螺旋CT双期扫描胰腺、动脉和门静脉的增强效果显著优于肝期成像，肿瘤-胰腺对比增强。
PURPOSE: To quantitatively evaluate and validate a two-phase helical computed tomographic (CT) protocol for evaluation of pancreatic tumors.MATERIALS AND METHODS: Twenty-seven patients with pathologically proved pancreatic adenocarcinomas prospectively underwent two-phase CT examination with helical acquisition during the pancreatic phase (40-70 seconds after infusion of intravenous contrast material at 3 mL/sec) and the hepatic phase (70-100 seconds after infusion). Mean CT attenuation values of tumor, bordering pancreas, and all major peripancreatic vessels were obtained for both time intervals.RESULTS: Mean tumor-pancreas contrast was significantly greater during the pancreatic phase (67 HU +/- 19) than the hepatic phase (39 HU +/- 16) (P < .001). This was the result of both greater enhancement of normal pancreas and lower tumor enhancement during the pancreatic phase. Opacification of all vascular structures, including the portal vein, was also greater during the pancreatic phase (P < .001).CONCLUSION: Two-phase helical CT with pancreatic phase acquisition provides statistically significantly better pancreatic, arterial, and portal venous enhancement than that of hepatic phase imaging, with improved tumor-pancreas contrast.