Ineffectiveness of lateral-wedge insoles on the improvement of pain and function for medial knee osteoarthritis: a meta-analysis of controlled randomized trials.
Ineffectiveness of lateral-wedge insoles on the improvement of pain and function for medial knee osteoarthritis: a meta-analysis of controlled randomized trials.
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外侧楔形鞋垫对改善内侧膝骨关节炎的疼痛和功能无效：对照随机试验的荟萃分析
DOI：
10.1007/s00402-018-3004-z
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发表时间：
2018-10
影响因子：
2.3
通讯作者：
Zhang C
中科院分区：
文献类型：
--
作者：
Zhang J;Wang Q;Zhang C
该研究旨在评估外侧楔形鞋垫在减轻疼痛和改善内侧膝关节骨关节炎患者的功能方面的作用。材料和方法从一开始到2017年10月，对Pubmed、Embase和Web of science等三个数据库进行了检索，以研究外侧楔形治疗在膝关节骨关节炎患者疼痛缓解和功能恢复方面的作用。采用固定效应模型或随机效应模型，基于CochraneQ统计和I2检验，对符合条件的研究进行汇总。此外，亚组分析按研究领域进行分层，并进一步设计敏感性分析，以评估强度的荟萃analys.Results10项研究，共938例，其中478例患者接受外侧楔形鞋垫和460例患者被设置为对照，被列入荟萃分析。汇总统计数据显示，与对照组相比，外侧楔形鞋垫治疗组的膝关节疼痛（SMD = − 0.21，95% CI − 0.50，0.08;P= 0.16）和膝关节功能（SMD = 0.22，95% CI − 0.27，0.70;P= 0.38）没有显著改善。然而，基于研究领域的亚组分析显示，与对照组相比，接受外侧楔形鞋垫的亚洲患者在疼痛减轻方面的结局良好。(SMD= − 0.88，95% CI − 1.59，− 0.17;P= 0.02）。在美国和其他地区的患者中未观察到显著改善。敏感性分析显示，当我们省略每项研究时，结果没有变化。没有显着的出版偏见被纳入study.ConclusionThough正常BMI的年轻亚洲患者，在一定程度上，外侧楔形鞋垫似乎是有帮助的。然而，没有证据表明种族与外侧楔形鞋垫在减轻疼痛方面的作用之间的关系。总而言之，根据目前的数据，外侧楔形鞋垫似乎对减轻膝关节疼痛和改善功能无效。
ObjectiveThe study aimed to evaluate the role of lateral-wedge insoles in pain reduction and functional improvement among patients with medial knee osteoarthritis.Materials and methodsThree databases including Pubmed, Embase, and Web of science were searched from inception until October 2017 for studies investigating the role of lateral-wedge treatment in pain relief and functional recovery among patients with knee osteoarthritis. Eligible studies were pooled using fixed effect model or random-effects model based on CochraneQstatistic andI2test. Moreover, subgroup analysis stratified by research area was performed, and sensitivity analysis was further designed to evaluate the strength of the meta-analysis.ResultsTen studies with a total of 938 patients, of which 478 patients received lateral-wedge insoles and 460 patients were set as control, were included in the meta-analysis. The pooled statistics did not show significant improvement in knee pain (SMD = − 0.21, 95% CI − 0.50, 0.08;P= 0.16) and knee function (SMD = 0.22, 95% CI − 0.27, 0.70;P= 0.38) in lateral-wedge insoles treatment group compared with controls. However, subgroup analysis based on research area revealed a favorable outcome toward Asian patients who received lateral-wedge insoles in pain reduction when compared with control group. (SMD = − 0.88, 95% CI − 1.59, − 0.17;P= 0.02). No significant improvement was observed among patients in USA and other areas. Sensitivity analysis showed unchanged results when we omitted each study. No significant publication bias was observed among the included studies.ConclusionThough for young Asian patients within normal BMI, to some extent, the lateral-wedge insoles seems to be helpful. However, there was no evidence to demonstrate the relationship between race and role of lateral-wedge insoles on pain reduction. All in all, based on current data, lateral-wedge insoles appear to be ineffective at attenuating knee pain and function improvement.
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DOI：
10.1002/art.23326
发表时间：
2008-03-15
期刊：
ARTHRITIS & RHEUMATISM-ARTHRITIS CARE & RESEARCH
影响因子：
--
作者：
Hinman, Rana S.;Payne, Craig;Bennell, Kim L.
通讯作者：
Bennell, Kim L.
影响因子：
2.8
作者：
Barrios, Joaquin A.;Butler, Robert J.;Crenshaw, Jeremy R.;Royer, Todd D.;Davis, Irene S.
通讯作者：
Davis, Irene S.
影响因子：
2.4
作者：
Nakajima, Kohei;Kakihana, WataFu;Fukui, Naoshi
通讯作者：
Fukui, Naoshi
影响因子：
7
作者：
Maillefert, JF;Hudry, C;Dougados, M
通讯作者：
Dougados, M
影响因子：
1.5
作者：
Rani, Nicola;Sabbioni, Giacomo;Dallari, Dante
通讯作者：
Dallari, Dante