Bond Strength of Resin to Acid-etched Dentin Studied by 13C NMR: Interaction between N-methacryloyl-ω-Amino Acid Primer and Dentinal Collagen
Bond Strength of Resin to Acid-etched Dentin Studied by 13C NMR: Interaction between N-methacryloyl-ω-Amino Acid Primer and Dentinal Collagen
复制标题
通过 13C NMR 研究树脂与酸蚀牙本质的结合强度：N-甲基丙烯酰-ω-氨基酸底漆与牙本质胶原蛋白之间的相互作用
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发表时间：
2000
期刊：
影响因子：
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通讯作者：
K. Nemoto
中科院分区：
文献类型：
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作者：
N. Nishiyama;T. Asakura;K. Suzuki;K. Komatsu;K. Nemoto
将亲水性甲基丙烯酸酯底漆应用于酸蚀牙本质增加了树脂与酸蚀牙本质的粘结强度。然而，树脂通过底漆与牙本质胶原结合的机制仍有待确定。在开发出更有效的粘结剂前，我们必须了解粘结剂对牙本质胶原的吸附行为。本研究的目的是确定N-甲基丙烯酰-ω-氨基酸（NMwA）引物的5种衍生物如何增强树脂与酸蚀牙本质的结合。通过13 C NMR技术研究了NMwA引物与牙本质胶原之间的相互作用，包括观察自旋-晶格弛豫时间T1。当牙本质胶原被分散到NMwA溶液中时，归因于NMwA分子中的酰胺和羧酸的两个羰基碳的T1值显著降低。这一结果是由于NMwA分子中的酰胺基和羧酸基与牙本质胶原分子之间的相互作用。随着NMωA分子中亚甲基数目的增加，这些羰基碳的T1值降低。随着NMwA分子中亚甲基数目的增加，相互作用变得更强。此外，树脂的酸蚀牙本质与NMwA底漆的粘结强度增加的酰胺羰基碳的T1值的降低。通过13 C NMR技术测定的NMwA引物与牙本质胶原分子的相互作用的强度显示出与树脂与用NMwA引物处理的酸蚀牙本质的结合强度直接相关。
The application of the hydrophilic methacrylate primer to acid-etched dentin increases the bond strength of the resin to the acid-etched dentin. However, the mechanism for the bonding of the resin to dentinal collagen through the primer remains to be determined. Before a more effective adhesive primer can be developed, we must understand the adsorption behavior of the primer to the dentinal collagen. The purpose of this study was to determine how 5 derivatives of N-methacryloyl-ω-amino acid (NMwA) primers enhance the bonding of the resin to acid-etched dentin. The interaction between the NMwA primers and dentinal collagen was studied by the 13C NMR technique, including the observation of spin-lattice relaxation times, T 1. When the dentinal collagen was dispersed into the NMwA solution, the T 1 values of the two carbonyl carbons attributed to the amide and the carboxylic acid in the NMwA molecule decreased dramatically. This result was due to the interaction between the amide group and the carboxylic acid group in the NMwA molecule and the dentinal collagen molecule. The T 1 values of these carbonyl carbons decreased when the number of methylene groups in the NMωA molecule increased. The interaction became stronger as the number of methylene groups in the NMwA molecule was increased. Further, the bond strength of the resin to the acid-etched dentin primed with NMwA increased with a decrease in the T 1 value of the amide carbonyl carbon. The strength of the interaction of the NMwA primer to the dentinal collagen molecule, determined by the 13C NMR technique, showed a direct correlation with the bond strength of the resin to acid-etched dentin that was treated with the NMwA primer.