Encoding of vestibular and optic flow cues to self-motion in the posterior superior temporal polysensory area
Encoding of vestibular and optic flow cues to self-motion in the posterior superior temporal polysensory area
复制标题
前庭和光流线索编码到后上颞多感觉区的自我运动
DOI：
10.1113/jp281913
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发表时间：
2021
期刊：
影响因子：
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通讯作者：
Chen Aihua
中科院分区：
文献类型：
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作者：
Zhao Bin;Zhang Yi;Chen Aihua
关键点后颞上多感觉区（STPp）的神经元对前庭、视流和视觉-前庭组合刺激表现出显着的方向选择性。与背内侧颞上区相比，STPp的视觉潜伏期较慢，但前庭潜伏期较快。STPp中组合刺激下的航向偏好通常以视觉信号为主。当前庭和视觉同时刺激时，STPp中观察到跨模态增强。摘要：人类神经影像数据表明，上颞多感觉区（STP）可能参与方向计算过程中的前庭视觉交互作用，但尚未在猕猴中检查方向选择性。在这里，我们使用虚拟现实系统研究了猕猴 STP 中光流和前庭信号的收敛情况，发现 6.3% 的 STP 神经元表现出多感觉反应，视觉和前庭方向偏好以大致相等的比例一致或相反。 STP 中前庭调节细胞的百分比 (18.3%) 远小于视觉调节细胞的百分比 (30.4%)。前庭调节强度通常弱于视觉条件。 STPp 中的视觉潜伏期明显慢于背侧内侧上颞区 (MSTd)，但前庭潜伏期明显快于 MSTd。在双峰条件下，STP细胞的反应以视觉信号为主，视觉方向偏好不受前庭信号影响，但反应幅度受前庭信号以亚加性方式调节。
Key pointsNeurons in the posterior superior temporal polysensory area (STPp) showed significant directional selectivity in response to vestibular, optic flow and combined visual–vestibular stimuli.By comparison to the dorsal medial superior temporal area, the visual latency was slower in STPp but the vestibular latency was faster.Heading preferences under combined stimulation in STPp were usually dominated by visual signals.Cross‐modal enhancement was observed in STPp when both vestibular and visual cues were presented together at their heading preferences.AbstractHuman neuroimaging data implicated that the superior temporal polysensory area (STP) might be involved in vestibular–visual interaction during heading computations, but the heading selectivity has not been examined in the macaque. Here, we investigated the convergence of optic flow and vestibular signals in macaque STP by using a virtual‐reality system and found that 6.3% of STP neurons showed multisensory responses, with visual and vestibular direction preferences either congruent or opposite in roughly equal proportion. The percentage of vestibular‐tuned cells (18.3%) was much smaller than that of visual‐tuned cells (30.4%) in STP. The vestibular tuning strength was usually weaker than the visual condition. The visual latency was significantly slower in STPp than in the dorsal medial superior temporal area (MSTd), but the vestibular latency was significantly faster than in MSTd. During the bimodal condition, STP cells’ response was dominated by visual signals, with the visual heading preference not affected by the vestibular signals but the response amplitudes modulated by vestibular signals in a subadditive way.