Predator strike shapes antipredator phenotype through new genetic interactions in water striders.
Predator strike shapes antipredator phenotype through new genetic interactions in water striders.
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DOI：
10.1038/ncomms9153
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发表时间：
2015-09-01
影响因子：
16.6
通讯作者：
Khila A
中科院分区：
文献类型：
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作者：
Armisén D;Refki PN;Crumière AJ;Viala S;Toubiana W;Khila A
新的遗传相互作用是如何进化的，在什么样的选择压力下，以及它们如何塑造适应性特征，往往是未知的。在这里，我们揭示了行为和发育的遗传机制，使水的生存攻击底部打击食肉动物。长的中腿，反捕食策略的关键，是通过一个谱系特异性的Hox蛋白Ultrabithorax（Ubx）和一个新的靶基因称为小母猪之间的相互作用形成的。腿形态的差异通过在Ubx控制下调节中腿和后腿之间的小母猪差异表达来建立。此外，通过镀金RNAi击倒产生的短腿水蜘蛛在捕食测试中表现出降低的性能。因此，新的Ubx-镀金相互作用的演变有助于塑造腿，使水<$鱼能够躲避捕食者的攻击。这些数据表明，与新的猎物-捕食者相互作用相关的趋异选择如何有利于新的遗传相互作用的进化，并推动适应性进化。理解生态相关性状进化的机制是具有挑战性的。在这里，作者表明，Hox蛋白Ultrabithorax及其靶基因gilt的变化有助于水虻中长-中腿的进化，这是逃避捕食者的关键特征。
How novel genetic interactions evolve, under what selective pressures, and how they shape adaptive traits is often unknown. Here we uncover behavioural and developmental genetic mechanisms that enable water striders to survive attacks by bottom-striking predators. Long midlegs, critical for antipredator strategy, are shaped through a lineage-specific interaction between the Hox protein Ultrabithorax (Ubx) and a new target gene called gilt. The differences in leg morphologies are established through modulation of gilt differential expression between mid and hindlegs under Ubx control. Furthermore, short-legged water striders, generated through gilt RNAi knockdown, exhibit reduced performance in predation tests. Therefore, the evolution of the new Ubx–gilt interaction contributes to shaping the legs that enable water striders to dodge predator strikes. These data show how divergent selection, associated with novel prey–predator interactions, can favour the evolution of new genetic interactions and drive adaptive evolution. Understanding the mechanism underlying the evolution of ecologically relevant traits is challenging. Here the authors show that changes in the Hox protein Ultrabithorax and its target gene gilt contribute to the evolution of long-mid-legs in water striders, a critical trait to escape predators.