Aqueous self-assembly of a charged BODIPY amphiphile via nucleation-growth mechanism
Aqueous self-assembly of a charged BODIPY amphiphile via nucleation-growth mechanism
复制标题
DOI：
10.1039/c5cp00207a
复制
发表时间：
2015-01-01
影响因子：
3.3
通讯作者：
Chen, Zhijian
中科院分区：
文献类型：
--
作者：
Yang, Le;Fan, Gang;Chen, Zhijian
合成了一种新的两亲性硼-二吡咯亚甲基（BODIPY）染料1，其中间位具有疏水楔形结构，硼位具有两个亲水阳离子结构。利用温度和浓度依赖的紫外/维斯光谱研究了染料在水中的自组装过程。使用两种不同的模型（分别由货车der Schoot等人和Goldstein等人开发）对协同超分子聚合的数据进行详细分析，清楚地表明染料1聚集的成核-生长机制和核尺寸（约1.5 μ m）。12-18个分子）和协同因子（ca. 0.01）可以导出。通过透射电子显微镜、扫描共聚焦显微镜和X-射线衍射的进一步研究揭示了具有多层壁结构的聚集体的独特的囊泡形态。同时，这些染料囊泡表现出独特的光学特性，即红移尖锐的吸收带，窄的发射线宽，并增加荧光量子产率，与单体染料相比。
A new amphiphilic boron-dipyrromethene (BODIPY) dye 1 with a hydrophobic wedge at the meso-position and two hydrophilic cationic moieties at boron was synthesized. Temperature- and concentration-dependent UV/Vis spectroscopic studies in water were conducted to explore the self-assembly process of the dye. Detailed analysis of the data using two different models (developed by Van der Schoot et al. and Goldstein et al. respectively) for cooperative supramolecular polymerization indicates distinctly a nucleation-growth mechanism of the aggregation of dye 1 and the nucleus size (ca. 12-18 molecules) and a cooperativity factor (ca. 0.01) could be derived. Further investigation by transmission electron microscopy, scanning confocal microscopy, and X-ray diffraction revealed a unique vesicular morphology of the aggregates with multilamellar wall structure. Meanwhile, these dye vesicles exhibit unique optical characteristics, i.e. red-shifted sharp absorption band, narrowed emission linewidth, and increase in fluorescence quantum yield, as compared with the monomeric dye.