The reaction of bone to self-curing acrylic cement. A long-term histological study in man.
The reaction of bone to self-curing acrylic cement. A long-term histological study in man.
复制标题
骨对自固化丙烯酸水泥的反应。
DOI：
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发表时间：
1970
影响因子：
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通讯作者：
John Charnley
中科院分区：
文献类型：
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作者：
John Charnley
1.骨水泥交界处的组织学状态的一般图片，长达7年的植入后，作为23个人体标本的研究结果。2.从骨水泥到骨的载荷传递通过新形成的纤维软骨介质在孤立点发生。3.很明显，这种纤维软骨是在对纤维组织的机械压力下产生的，纤维组织在骨水泥和下层骨之间受到压缩。4.在这些载荷传递部位，骨水泥表面和新形成的纤维软骨之间存在直接接触。5.承重纤维软骨经常显示从下面的骨延伸到它的骨化区域。6.当与骨水泥接触的软组织太厚或太脆弱而无法传递载荷时，骨水泥表面会覆盖一层薄的巨细胞质。7.未见巨细胞聚集形成肉芽肿或干酪样区。8.在骨水泥表面10微米范围内可能发生脂肪储存，表明无化学刺激。
1. A general picture of the histological state of the bone-cement junction, up to seven years after implantation, is presented as a result of the study of twenty-three human specimens. 2. The transmission of load from cement to bone occurs at isolated points through the medium of newly formed fibrocartilage. 3. It is clear that this fibrocartilage has been produced in response to mechanical pressure on fibrous tissue which has undergone compression between cement and underlying bone. 4. Direct contact exists between the surface of the cement and the newly formed fibrocartilage at these sites of load transmission. 5. Load-bearing fibrocartilage frequently shows areas of ossification extending into it from the underlying bone. 6. Where soft tissues in contact with cement are too thick or too delicate for load transmission a thin layer of giant-cell cytoplasm coats the cement surface. 7. No collections of giant cells to form granulomatous or caseating areas have been seen. 8. Fat storage, indicating the absence of chemical irritation, can occur within ten microns of the cement surface.