Fetal weight gain in a serially scanned high-risk population

Fetal weight gain in a serially scanned high-risk population
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DOI:
10.1046/j.1469-0705.1998.11010039.x
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发表时间:
1998-01-01
影响因子:
7.1
通讯作者:
van Geijn, HP
van Geijn, HP
中科院分区:
医学1区
文献类型:
--
作者:
de Jong, CLD;Gardosi, J;van Geijn, HP

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生理和病理变量影响胎儿生长。本研究旨在评估生理变量对高危人群正常结局胎儿体重增加的影响。共有121例妊娠在妊娠晚期进行了3-13次(中位数为8次)超声扫描。根据标准公式计算胎儿体重。计算胎儿在30,34和38周时的估计体重以及分娩前最后2周的每天生长情况,并比较根据生理特征(如母亲身高,母亲体重,胎次和胎儿性别)定义的亚组。各生理参数的生长曲线存在差异。在整个妊娠晚期,母亲的身高和体重与估计的胎儿体重显著相关,但在出生前最后2周,每天的生长没有显著差异。相比之下,以胎次和胎儿性别定义的亚组在妊娠晚期胎儿体重没有显着差异,但多胎和男性胎儿出生前的日生长率明显较高。生理因素影响胎儿体重增加,在高危妊娠监测胎儿生长时需要考虑到这一点。
Physiological as well as pathological variables influence fetal growth. This study was undertaken to assess the influence of physiological variables on fetal weight gain in a high-risk population with normal outcome. A total of 121 pregnancies had 3-13 (median 8) ultrasound scans in the third trimester. Estimated fetal weight was calculated according to standard formulae. The estimated fetal weight at 30, 34 and 38 weeks and growth per day in the last 2 weeks prior to delivery were calculated and compared between subgroups defined on physiological characteristics, such as maternal height, maternal weight, parity and fetal sex.There were differences in growth curves for each of the physiological parameters studied. Maternal height and weight were significantly related to the estimated fetal weight throughout the third trimester but there were no significant differences in growth per day in the last 2 weeks before birth. In contrast, subgroups defined by parity and fetal sex did not show significant fetal weight differences in the third trimester, but the daily growth rate prior to birth was significantly higher for multiparae and male fetuses. Physiological factors affect fetal weight gain and need to be taken into account when fetal growth is monitored in high-risk pregnancies.