Assembly and functions of the spindle pole body in budding yeast.
Assembly and functions of the spindle pole body in budding yeast.
复制标题
DOI：
10.1016/0168-9525(93)90247-f
复制
发表时间：
1993-09
期刊：
影响因子：
--
通讯作者：
M. Winey;Breck Byers
中科院分区：
文献类型：
--
作者：
M. Winey;Breck Byers
纺锤体极体（SPB）在酵母和多种其他低等真核生物中充当中心体。在酿酒酵母中，这种细胞器控制细胞中所有微管的组装，不仅充当有丝分裂或减数分裂纺锤体的极点，而且充当细胞质微管发出的位点。 SPB 的独特结构允许定义其在酵母生命周期所有阶段的复制和行为的离散阶段。与遗传分析相结合，对酵母 SPB 的研究为了解该真核生物模型中控制中心体行为的机制提供了见解。
The spindle pole body (SPB) serves as the centrosome in yeast and in a variety of other lower eukaryotes. In Saccharomyces cerevisiae, this organelle controls the assembly of all microtubules in the cell, acting not only as a pole of the mitotic or meiotic spindle but also as the site from which cytoplasmic microtubules emanate. The distinctive structure of the SPB has permitted definition of discrete stages in its duplication and behavior at all stages of the yeast life cycle. In association with genetic analyses, studies of the yeast SPB are providing insights into the mechanisms that control centrosomal behavior in this model eukaryote.