Lightweight, compact, and high-performance 3T MR system for imaging the brain and extremities.
Lightweight, compact, and high-performance 3T MR system for imaging the brain and extremities.
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DOI：
10.1002/mrm.27175
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发表时间：
2018-11
影响因子：
3.3
通讯作者：
Bernstein MA
中科院分区：
文献类型：
--
作者：
Foo TKF;Laskaris E;Vermilyea M;Xu M;Thompson P;Conte G;Van Epps C;Immer C;Lee SK;Tan ET;Graziani D;Mathieu JB;Hardy CJ;Schenck JF;Fiveland E;Stautner W;Ricci J;Piel J;Park K;Hua Y;Bai Y;Kagan A;Stanley D;Weavers PT;Gray E;Shu Y;Frick MA;Campeau NG;Trzasko J;Huston J 3rd;Bernstein MA
构建和评估一种体积小、重量轻、高性能的3.0T MRI扫描仪，用于高级脑成像，其图像质量等于或优于传统的全身临床3.0T MRI扫描仪，同时大幅降低安装成本。在充气密封系统中，仅使用小于12升的液氦和标准的NbTi线的传导冷却磁体，重量约为2000公斤。研究人员开发了一种内径42厘米、横轴不对称的梯度线圈，为患者提供头部和四肢检查的通道，同时最大限度地减少磁体梯度相互作用对图像质量的不利影响。梯度线圈的设计目的是利用现成的1 MVA梯度驱动器，在每个梯度轴上以700 T/m/s的摆速同时实现80 mT/m的峰值梯度振幅。在16例使用T2W-3D-FLAIR的患者的解剖成像中，在紧凑3T和全身3T之间进行比较，图像质量在几个指标上被评估为等于或更好。充分利用700吨/米/秒的高旋转速率和80吨/米的最大梯度振幅的能力，提高了EPI、扩散成像和大脑解剖成像的图像质量。紧凑的3T MRI系统自2016年3月以来一直在梅奥诊所连续运行。迄今为止，已经完成了200多项患者研究，其中包括96项与临床3T全身MRI的比较研究。增加的梯度性能可靠地导致始终如一地提高图像质量。
To build and evaluate a small-footprint, lightweight, high-performance 3.0T MRI scanner for advanced brain imaging with image quality that is equal to or better than conventional whole-body clinical 3.0T MRI scanners, while achieving substantial reductions in installation costs. A conduction-cooled magnet that uses only < 12 liters of liquid helium in a gas-charged sealed system, and standard NbTi wire and weighs ~2000 kg was developed. A 42-cm inner diameter gradient coil with asymmetric transverse axes was developed to provide patient access for head and extremity exams, while minimizing magnet-gradient interactions that adversely impact image quality. The gradient coil was designed to achieve simultaneous operation of 80 mT/m peak gradient amplitude at a slew rate of 700 T/m/s on each gradient axis using readily-available, 1 MVA gradient drivers. In a comparison of anatomical imaging in 16 patients using T2W-3D-FLAIR between the compact 3T and whole-body 3T, image quality was assessed as equivalent to or better across several metrics. The ability to fully utilize a high slew rate of 700 T/m/s simultaneously with 80 mT/m maximum gradient amplitude resulted in improvements in image quality across EPI, diffusion imaging, and anatomical imaging of the brain. The compact 3T MRI system has been in continuous operation at the Mayo Clinic since March, 2016. To date, over 200 patient studies have been completed, including 96 comparison studies with a clinical 3T whole-body MRI. The increased gradient performance has reliably resulted in consistently improved image quality.
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影响因子：
4.4
作者：
Liu, Guoxiang;Ogawa, Seiji
通讯作者：
Ogawa, Seiji
影响因子：
3.3
作者：
JEZZARD, P;BALABAN, RS
通讯作者：
BALABAN, RS
影响因子：
4.4
作者：
Tan, Ek T.;Lee, Seung-Kyun;Foo, Thomas K. F.
通讯作者：
Foo, Thomas K. F.
影响因子：
5.7
作者：
Setsompop K;Kimmlingen R;Eberlein E;Witzel T;Cohen-Adad J;McNab JA;Keil B;Tisdall MD;Hoecht P;Dietz P;Cauley SF;Tountcheva V;Matschl V;Lenz VH;Heberlein K;Potthast A;Thein H;Van Horn J;Toga A;Schmitt F;Lehne D;Rosen BR;Wedeen V;Wald LL
通讯作者：
Wald LL
影响因子：
19.7
作者：
SCHENCK, JF;JOLESZ, FA;VOSBURGH, KG
通讯作者：
VOSBURGH, KG